Protein Info for UW163_RS13445 in Ralstonia solanacearum UW163

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 transmembrane" amino acids 41 to 60 (20 residues), see Phobius details amino acids 66 to 86 (21 residues), see Phobius details amino acids 103 to 125 (23 residues), see Phobius details amino acids 137 to 156 (20 residues), see Phobius details PF06580: His_kinase" amino acids 185 to 264 (80 residues), 73 bits, see alignment E=2e-24 PF02518: HATPase_c" amino acids 283 to 377 (95 residues), 41.6 bits, see alignment E=1.5e-14

Best Hits

KEGG orthology group: None (inferred from 90% identity to rso:RSc1351)

Predicted SEED Role

"Autolysin sensor kinase (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (414 amino acids)

>UW163_RS13445 sensor histidine kinase (Ralstonia solanacearum UW163)
MRESPRFSPGAPSSKIGRMFSNVSLPPLAECLRIAVRGLRVLAGIAAINTGIAAVLAFGI
KPDDTFWHDFVYSQAIGLSMWLLIDIPRHLLWGRGVPSRRVFPWIVVAAVLIGVPFGQWV
ARLILCTGDQPWRADSLRMSFIIAMLAALGAMYFYWSRGKLAALQRQAALDALEREEAEK
QVVRAQLMALQAQVEPHFIFNVLAHVDVLIARDPAGARRLLQHLIGFLRTSLAHARAEQC
TLAQEFALLRAYLDIQALRFGARLQFSLALDEAIADLVIPPMLIQPLVENAVVHGIEPSR
EGGSIALSARRDGDRLLLEVRDTGVGFGRDARPGMGSGLGLTHVRERLSRLFDADARLTL
AETVPHGVSVTVELPLAHDAVGAEVSGAPAPQWRCRFSRPAVAPALAPRAPAGT