Protein Info for UW163_RS12055 in Ralstonia solanacearum UW163

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 47 to 69 (23 residues), see Phobius details amino acids 76 to 99 (24 residues), see Phobius details amino acids 136 to 159 (24 residues), see Phobius details amino acids 164 to 185 (22 residues), see Phobius details amino acids 232 to 251 (20 residues), see Phobius details amino acids 265 to 286 (22 residues), see Phobius details amino acids 298 to 322 (25 residues), see Phobius details amino acids 328 to 349 (22 residues), see Phobius details amino acids 361 to 383 (23 residues), see Phobius details amino acids 390 to 411 (22 residues), see Phobius details PF07690: MFS_1" amino acids 15 to 373 (359 residues), 186 bits, see alignment E=1e-58 amino acids 306 to 417 (112 residues), 35.2 bits, see alignment E=7.1e-13 PF00083: Sugar_tr" amino acids 38 to 183 (146 residues), 22.9 bits, see alignment E=3.7e-09

Best Hits

KEGG orthology group: K08191, MFS transporter, ACS family, hexuronate transporter (inferred from 98% identity to rso:RSc1080)

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (432 amino acids)

>UW163_RS12055 MFS transporter (Ralstonia solanacearum UW163)
MKTIKGLRWWIIALVCLGTITNYLARNSLGVLAPQLKTELGMSTQQYSYVVGAFQVGYTI
MQPVCGFIVDLIGLRIGFAVFAVLWSIAGCLHAGASGWLSLASFRGLMGLTEAAAIPSGM
KAVAEWFPDKEKSVAVGYFNAGTSLGALLAPPLVVFLSLRYGWQSAFVVTGALGFVWAAL
WYAFYRSPRDHAQLSAAEHDRIVGGQIRSAGAVRGKRPVREVVTSRRFWAIALPRFFAEP
AWQTFSFWIPLYLSSARHMDLKEIALFAWLPFLAADLGGLLGGYLSPFFMKCFRVPLVWS
RVCGVVLGAFLMIGPACIGLVASPYQAIALFCVGGFAHQMISTLVNTLSADVFDPEEVGT
ASGFAGMAAWIGGLGFSLMVGALADTVGYGPLFGLLGAFDLIGATLLILLIRGQSQEERA
ARQMQHTLSASH