Protein Info for UW163_RS11975 in Ralstonia solanacearum UW163

Annotation: beta-N-acetylhexosaminidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00933: Glyco_hydro_3
  • amino acids 28 to 316 (289 residues), 245 bits, E=6.9e-77

Best Hits

Swiss-Prot: 62% identical to NAGZ_BORBR: Beta-hexosaminidase (nagZ) from Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)

KEGG orthology group: K01207, beta-N-acetylhexosaminidase [EC: 3.2.1.52] (inferred from 96% identity to rsc:RCFBP_20409)

Predicted SEED Role

"Beta N-acetyl-glucosaminidase (EC 3.2.1.52)" (EC 3.2.1.52)

MetaCyc Pathways

• peptidoglycan recycling II (8/10 steps found)
• peptidoglycan recycling I (10/14 steps found)
• chitin degradation II (Vibrio) (2/6 steps found)
• chitin degradation III (Serratia) (2/7 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Glycosaminoglycan degradation
• Glycosphingolipid biosynthesis - ganglio series
• Glycosphingolipid biosynthesis - globo series
• Nucleotide sugars metabolism
• Other glycan degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.52

Protein Sequence (350 amino acids)

>UW163_RS11975 beta-N-acetylhexosaminidase (Ralstonia solanacearum UW163)
MNSITKQQKRPGPIVLDVVGLELAPDDVRRIVHPLTGGVILFARNFESRAQLAALTAAIR
AVRDDVLICIDHEGGRVQRARRDGFTHLPAMAALGQLWERDVLAATRAATACGYVLAAEL
RACDIDLSFTPVLDLDYGTSSVIGDRAFHRDPRVVTMLANHLTLGLRLAGMANCGKHFPG
HGWVQADSHVAVPVDERPLQAILDEDAQPYGWMGIGLQSVMPAHVIYPAVDPNPAGFSRF
WLQDILRTHYNFDGVIFSDDLSMEGASVAGSVVDGARAALAAGCDMVLICNAPDKADKLL
NELDVTMGKASQRRVRRLFGGKALKDWSKLLQQSAYRQALRTLREARLIA