Protein Info for UW163_RS10585 in Ralstonia solanacearum UW163

Annotation: xanthine dehydrogenase small subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02963: xanthine dehydrogenase, small subunit
  • amino acids 6 to 487 (482 residues), 699.8 bits, E=7.7e-215
• PF00111: Fer2
  • amino acids 13 to 62 (50 residues), 23.2 bits, 1e-08
• PF01799: Fer2_2
  • amino acids 86 to 165 (80 residues), 101 bits, E=6.4e-33
• PF00941: FAD_binding_5
  • amino acids 208 to 372 (165 residues), 167.8 bits, E=4.1e-53
• PF03450: CO_deh_flav_C
  • amino acids 382 to 486 (105 residues), 111.9 bits, E=3.1e-36

Best Hits

KEGG orthology group: K13481, xanthine dehydrogenase small subunit [EC: 1.17.1.4] (inferred from 96% identity to rsc:RCFBP_11294)

Predicted SEED Role

"Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A (1.17.1.4)" in subsystem Purine Utilization

MetaCyc Pathways

• purine nucleotides degradation I (plants) (10/12 steps found)
• adenosine nucleotides degradation I (7/8 steps found)
• guanosine nucleotides degradation II (4/4 steps found)
• superpathway of purines degradation in plants (14/18 steps found)
• superpathway of guanosine nucleotides degradation (plants) (5/6 steps found)
• adenosine nucleotides degradation II (4/5 steps found)
• guanosine nucleotides degradation I (3/4 steps found)
• guanosine nucleotides degradation III (3/4 steps found)
• inosine 5'-phosphate degradation (3/4 steps found)
• purine nucleotides degradation II (aerobic) (8/11 steps found)
• ureide biosynthesis (5/7 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• caffeine degradation III (bacteria, via demethylation) (1/7 steps found)
• theophylline degradation (1/9 steps found)
• caffeine degradation IV (bacteria, via demethylation and oxidation) (1/10 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.17.1.4

Use Curated BLAST to search for 1.17.1.4

Protein Sequence (511 amino acids)

>UW163_RS10585 xanthine dehydrogenase small subunit (Ralstonia solanacearum UW163)
METQSIRFFHRGQVRTVTHAPITRTVLQYLREDARCTGTKEGCAEGDCGACTVVLGELRQ
DGGVELKAVNACIQFLPTLEGKALFTVEDVRGKDGTLHPVQQAMVECHGSQCGFCTPGFV
MSLYALYENTGAGAAASPPPSRETLCDALTGNLCRCTGYRPIIDAGQRMYELPAPAGIDR
TQLAETLRALQRADTFCYAPAGIAPAARFYAPRTLSAFAALKAARPDIRILAGSTDVGLW
VTKQFRELGDLLYVGQVAELYALDQRDGWLEIGAAVSLEKAYAFLAQDYPELTEMWRRFA
SLPIRNAGTLGGNIANGSPIGDSAPALIALGTRVVLQHGEARRELPLEDLYLAYMKNAMA
PGEFVAGLRVPARAGRDALRLRTYKLSKRFDEDISAVCAALAIELDGKDGNTIVRSARIA
YGGMAATSKRAAETEAAITGQPWNEATARAAMAAMSRDYTPLTDMRASEHYRRTAAANTV
YRFWLETRPDAPLQAAQINVRAVEPDTRAVA