Protein Info for UW163_RS10490 in Ralstonia solanacearum UW163

Annotation: purine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 468 transmembrane" amino acids 23 to 48 (26 residues), see Phobius details amino acids 55 to 77 (23 residues), see Phobius details amino acids 84 to 102 (19 residues), see Phobius details amino acids 109 to 129 (21 residues), see Phobius details amino acids 139 to 162 (24 residues), see Phobius details amino acids 183 to 203 (21 residues), see Phobius details amino acids 211 to 235 (25 residues), see Phobius details amino acids 257 to 283 (27 residues), see Phobius details amino acids 337 to 355 (19 residues), see Phobius details amino acids 365 to 386 (22 residues), see Phobius details amino acids 398 to 420 (23 residues), see Phobius details amino acids 428 to 447 (20 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 19 to 445 (427 residues), 395.9 bits, see alignment E=2.3e-122 PF00860: Xan_ur_permease" amino acids 22 to 415 (394 residues), 343.5 bits, see alignment E=7e-107 TIGR03173: xanthine permease" amino acids 25 to 447 (423 residues), 540.4 bits, see alignment E=2.5e-166

Best Hits

KEGG orthology group: K03458, nucleobase:cation symporter-2, NCS2 family (inferred from 96% identity to rsl:RPSI07_1315)

Predicted SEED Role

"Xanthine/uracil transporter" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (468 amino acids)

>UW163_RS10490 purine permease (Ralstonia solanacearum UW163)
MASTLAAPPADLTSERVASARLLALGLQHVLVMYAGTVAVPLIVGGALHLPKEQLAFLIN
ADLFAAGLATLIQSFGLWKFGIRMPVMMGVTFASVGPMIAIGSDPGSGLLGIYGAVIAAG
LFGIAVAPLMGRVLGLFPPVVTGTVITLIGVSLMGVGINWAAGGQPTLKTMVDGVPWTVP
NPAYGDPGGLAIALSVLVIILLLTKYGRGLIGNIAVLLGIVCGTLIAMAAGKVSFAGVAD
ADWMAVVTPLHFGMPTFHLGAIASMCVVMLITLVESTGMFLALAEITGKKLTPGDLTRGL
RADGLGSLIGGLFNTFPYTSFSQNVGLVTVTGVRSRFVAATGGVILIALGLFPKMAHVVA
SVPSFVLGGAGIVMFGMVAATGVRILGSIDFNRHRHNLFIVAIAIGFGMIPTLAPAFFQY
LPRWLEPVTHSGIVLGTLVAVILNLYYNGMQSTEHAMRAAAATTHGAE