Protein Info for UW163_RS09720 in Ralstonia solanacearum UW163

Annotation: HlyC/CorC family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 55 to 74 (20 residues), see Phobius details amino acids 98 to 118 (21 residues), see Phobius details amino acids 130 to 152 (23 residues), see Phobius details PF01595: CNNM" amino acids 5 to 195 (191 residues), 158.2 bits, see alignment E=2.6e-50 PF00571: CBS" amino acids 284 to 334 (51 residues), 30.5 bits, see alignment 5.6e-11 PF03471: CorC_HlyC" amino acids 348 to 425 (78 residues), 69.6 bits, see alignment E=2.8e-23

Best Hits

KEGG orthology group: None (inferred from 97% identity to rsc:RCFBP_11122)

Predicted SEED Role

"protein of unknown function DUF21"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (437 amino acids)

>UW163_RS09720 HlyC/CorC family transporter (Ralstonia solanacearum UW163)
MYVLVLVSLILVSAFFSASEIALTASRRTRLQTLADEGDGRALRILQLKDAPGNFFTVVQ
IGVNAVAILAGIIGERQISDTLAAWLADWLPQARAERFANLAGFVIVTSLFILLADLLPK
RLAVLYPERFALAIIGPMQGCLRVLRPVVWLFNGTAELILKLLGVPTQRIEQITTEDITA
MVGAGAEAGVLREHELTVIENVFELESRTVTSVMTVRDDIVYFTLDEPLESIKRKIVGQP
HAEYLVCRDDIDSVLGFIASKDILQQILSEESSAVIRNVGKHYNKNLLVLPDTLNLSQAL
ARFREMHERFGAVVNEYGLVVGVVTLDDIVGAVMGDILYLGEDEQIVRRDDGSCLVDGIT
PVADVKRAFNLDDLPGEHQVETIAGLVIYALKRIPKKSESIDIGPLHIEVLDIDNHRIDQ
LLVSRCVDAPDASAAAS