Protein Info for UW163_RS08150 in Ralstonia solanacearum UW163

Annotation: mechanosensitive ion channel family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 transmembrane" amino acids 30 to 49 (20 residues), see Phobius details amino acids 65 to 90 (26 residues), see Phobius details amino acids 96 to 126 (31 residues), see Phobius details PF00924: MS_channel_2nd" amino acids 114 to 179 (66 residues), 67.5 bits, see alignment E=4.5e-23

Best Hits

KEGG orthology group: K03442, small conductance mechanosensitive channel (inferred from 97% identity to rsc:RCFBP_10785)

Predicted SEED Role

"Small-conductance mechanosensitive channel"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (298 amino acids)

>UW163_RS08150 mechanosensitive ion channel family protein (Ralstonia solanacearum UW163)
MAENLVDTTVNTASKYQAIVAQYATDVGMKILAAIAFWVIGRWLIHLAVRLVRGSLEHQK
VDPTVLRYVGSVITVTLNILLVIGILGYFGIQTTTFAALIAAAGVAIGMAWSGLLSNFAA
GAFLIVLRPFKVGDFVTAGGVTGTVKEIGLFATALNTPDNVVTLVGNNKIFSDTIQNYTV
NPYRRVELKAQLAGSADHRAAIALLKEKVGAIPNVLTDPPVDVEILEFNLVGPVLAVRPH
THNDHYWQVYFDTNRTIREALAEAGFPVPTPSQTLSVTMPTTLQGLAAVAQTQPTSVN