Protein Info for UW163_RS06845 in Ralstonia solanacearum UW163

Annotation: iron ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF13531: SBP_bac_11" amino acids 52 to 307 (256 residues), 59.4 bits, see alignment E=9.3e-20 PF01547: SBP_bac_1" amino acids 57 to 303 (247 residues), 52.6 bits, see alignment E=1.4e-17 PF13416: SBP_bac_8" amino acids 65 to 320 (256 residues), 78.4 bits, see alignment E=1.6e-25 PF13343: SBP_bac_6" amino acids 136 to 310 (175 residues), 61 bits, see alignment E=2.6e-20

Best Hits

KEGG orthology group: K02012, iron(III) transport system substrate-binding protein (inferred from 99% identity to rsc:RCFBP_10514)

Predicted SEED Role

"Putative ABC transporter, periplasmmic iron binding protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (367 amino acids)

>UW163_RS06845 iron ABC transporter substrate-binding protein (Ralstonia solanacearum UW163)
MLRGHFAPARAAVAVAVAALTLGTAAFAQVPAGYPASYADTIAAAKKEGKVVVYATTDTK
AADPLIKDFESLYPGVKVEYNDMNSSELYNRFISEQAAGGASADMMWNSSMDSQLKLAQT
YAMTYQSPEAASLPKWAVYKGLAYGTTYEPAVFLYNKRLVKDSEVPQTHADLAKLVSGQP
ERFKNKVTTYDIEKSAVGFMMAAQDNQDSPQYFDFIKAVGPNLVLQSSTGTMMERVASGE
NLLAYNILGSYAMARAKKDPSIGIVYPKDYTLVVSRVAMIAKKAQHPNAAKLWLDYILSK
RGQDILANKSDLHSLRDDVSGEATAAGLKQILGQSIKPIPVDESVLTFLEPKKRLDFIKQ
WRTAAGR