Protein Info for UW163_RS04890 in Ralstonia solanacearum UW163

Annotation: branched-chain amino acid ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 29 to 369 (341 residues), 201.9 bits, see alignment E=3.5e-63 PF13433: Peripla_BP_5" amino acids 36 to 333 (298 residues), 38.9 bits, see alignment E=8.6e-14 PF01094: ANF_receptor" amino acids 48 to 368 (321 residues), 98.5 bits, see alignment E=6.4e-32

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 98% identity to rsc:RCFBP_10168)

Predicted SEED Role

"Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (381 amino acids)

>UW163_RS04890 branched-chain amino acid ABC transporter substrate-binding protein (Ralstonia solanacearum UW163)
MKRKQLWVAAALCALAGGATTAASAQEVVKLGFAAPMTGAQAQYGKDMQNGVTLAIEEFN
ATKPKIAGKDVKFQLVSEDDQADPKTGTTVAQKLVDGGIKGMLGHFNSGTSIPASRVYNQ
AGIAQIAMATAPEYTKQGYKTTFRMMTSDTQQGSVVGTFAVKKLGYKNIAIVDDRTAYGQ
GLADEFEKAAKAAGATIVRREYTNDKASDFKAILTQIKSKSPDAVFYGGAEGQSAPLVKQ
MRELGMKSTLMSGEMSKTDDFIKLAGAPAAEGVVCSLAGLPLEQMPGGAGFRQRYEKRFG
STVQTYSPYAYDGAMALMKSMVAAGSSDPSKYLPILSATNTQGVTAKHYAYDDKGDLKDG
GITVYKVTGGKWVPLESVGGK