Protein Info for UW163_RS03360 in Ralstonia solanacearum UW163

Annotation: NAD-dependent epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 transmembrane" amino acids 236 to 256 (21 residues), see Phobius details PF01370: Epimerase" amino acids 7 to 204 (198 residues), 65.2 bits, see alignment E=9.7e-22 PF01073: 3Beta_HSD" amino acids 9 to 200 (192 residues), 31.7 bits, see alignment E=1.2e-11 PF13460: NAD_binding_10" amino acids 10 to 152 (143 residues), 41.6 bits, see alignment E=1.9e-14

Best Hits

KEGG orthology group: None (inferred from 99% identity to rsc:RCFBP_21285)

Predicted SEED Role

"Putative transmembrane oxidoreductase protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (312 amino acids)

>UW163_RS03360 NAD-dependent epimerase (Ralstonia solanacearum UW163)
MNPTRIVLPGGAGLVGQNLVARLKARGYTNLVVLDKHKANLEILRSVHPDVTAVFADLAE
PGDWERHFEGADAVVMLQAQIGAPTREPFVRNNIDSTRCVLDVIKRYDIPYTVHISSSVV
KSVGEDWYTETKREQEEIVLASGIKCVVLRPTLMFGWFDRKHLGWLSRFMQRVPVFPIPG
SGRYMRQPLYVGDFCNVIISCIDSRIQGQTFDITGLERVDYIDIIRQIKRATRAHCAIVR
IPYSLFYVLLKIYALFSKNPPFTADQLKALTAGDEFEVIDWEGIFAIRATPFAKAMEETF
NDPAYSHIALEF