Protein Info for UW163_RS02280 in Ralstonia solanacearum UW163

Annotation: acyl-CoA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 signal peptide" amino acids 33 to 34 (2 residues), see Phobius details amino acids 52 to 52 (1 residues), see Phobius details transmembrane" amino acids 35 to 51 (17 residues), see Phobius details amino acids 211 to 228 (18 residues), see Phobius details PF03279: Lip_A_acyltrans" amino acids 21 to 274 (254 residues), 39.4 bits, see alignment E=2.1e-14

Best Hits

KEGG orthology group: None (inferred from 94% identity to rsc:RCFBP_21053)

Predicted SEED Role

"Lysophospholipid acyltransferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (324 amino acids)

>UW163_RS02280 acyl-CoA synthetase (Ralstonia solanacearum UW163)
MKRTEWAQREERSNVLLLRAMTWISLRFGRRAGRAVLRVVALYFVLFSPSARRASRDYLR
RVLGRPARWRDVYRHLFTFGTTIHDRIYLMNGRFDLFDIRLQGDGLVHAALAEGQGVFLM
GAHLGSFEVVRAVGRTRPGTRIAVTMYEDNARRINAALAAINPAAKPDIIGLGRVDAMLR
VREALDANGMVGMLADRTLLREAGSSVQRMAFLGMPATFPLGPLHMAAMLKRRVLFMTGL
YRDGNRYDVHFEALADFSSVRREERAAAVQAALVRYVALLERYCRAAPYNWFNYFDFWQG
AETAGPHRDATPPDADLPATDEHP