Protein Info for UW163_RS01285 in Ralstonia solanacearum UW163

Annotation: MCE family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 transmembrane" amino acids 21 to 45 (25 residues), see Phobius details amino acids 120 to 136 (17 residues), see Phobius details PF02470: MlaD" amino acids 49 to 140 (92 residues), 44.2 bits, see alignment E=9.3e-16 amino acids 164 to 224 (61 residues), 40.8 bits, see alignment E=1.1e-14 amino acids 292 to 396 (105 residues), 52.2 bits, see alignment E=2.9e-18

Best Hits

KEGG orthology group: K06192, paraquat-inducible protein B (inferred from 99% identity to rsc:RCFBP_20872)

Predicted SEED Role

"Paraquat-inducible protein B" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (547 amino acids)

>UW163_RS01285 MCE family protein (Ralstonia solanacearum UW163)
MTDPVDTRDIPPPRRMKRKRWLPSLIWLVPIVALAVGATLMTRVILARGAQITVTFSSAE
GIEAGKTRVKYKSVDIGVVKDVGLTEDRSGAVVMIELTRDGKAFAVSDTRFWVVRPRVAA
GSISGLGTLLSGAYIGVDGGRAKERKSEFKGLDTPPAIYADTPGRQFTLHAADLGSLDTG
APVYFRRVRVGQVTSYDIDADGEGVTLHIFVNAPFDRFVTRSSRFWNASGIDLKLDASGL
KVDMQSLLTVALGGIAFQSPEDADRDPAPQNTEFQLVRNEAMALKDPEHVSQTVVMYFHR
SLRGLTVGAPVEFKGINVGEIKSIGIHYSKERHEFVLPVTAVLYPTRFGMAVRDDTAAHA
IEDTRAQFDTLISNGMRAQLKSASLLTGQQFVQLDFVEPADRGKTPPRFGQRERDGAYVF
PTADNPTDDIEAQIAGIVKKLNKVPFDQIGQDVHRALGSLDATLKQTEQLAKTVNNDLAP
QMKETLAEARRTLETARQTFSEDAPLQRNARDTLEQVAKAAASVRVLTDYLDRHPEALIR
GKAKDAQ