Protein Info for UW163_RS00835 in Ralstonia solanacearum UW163

Annotation: TetR/AcrR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 264 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 183 to 198 (16 residues), see Phobius details PF00440: TetR_N" amino acids 43 to 87 (45 residues), 57 bits, see alignment 2.6e-19 PF16859: TetR_C_11" amino acids 109 to 198 (90 residues), 41.7 bits, see alignment E=2.7e-14 PF14246: TetR_C_7" amino acids 114 to 193 (80 residues), 34.2 bits, see alignment E=4.5e-12 PF17932: TetR_C_24" amino acids 136 to 210 (75 residues), 27.3 bits, see alignment E=7.6e-10

Best Hits

KEGG orthology group: None (inferred from 98% identity to rsc:RCFBP_20716)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (264 amino acids)

>UW163_RS00835 TetR/AcrR family transcriptional regulator (Ralstonia solanacearum UW163)
MSQWCSLPTGSVAAVTAVTDRDPESSTKRWTRRKEARPQELAAAALSLFVARGFAATRLE
DVAAAAGVSKGTVYLYFANKVELFKAVVQENLLPILAEGEALIDTFEGTSEALLHEILMG
WWELIGESPASGLTKLLMAEAGNFPDLAQYYHEAVIQRCDRLFARILKRGVARGEFREAD
IDMTTLALVAPMLFLMMWKHSFGPCSHRELDPKAFVTHLVALMLHGLLRNPVPGTAIPPP
PPLACQPWRPMPADDTGADEGAAP