Protein Info for UW163_RS00705 in Ralstonia solanacearum UW163

Annotation: general secretion pathway protein GspH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 transmembrane" amino acids 16 to 39 (24 residues), see Phobius details PF07963: N_methyl" amino acids 13 to 35 (23 residues), 30.5 bits, see alignment (E = 1.9e-11) TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 14 to 35 (22 residues), 28.6 bits, see alignment (E = 4.2e-11) PF12019: GspH" amino acids 51 to 179 (129 residues), 50.3 bits, see alignment E=3.1e-17

Best Hits

KEGG orthology group: K08084, type IV fimbrial biogenesis protein FimT (inferred from 95% identity to rsc:RCFBP_20691)

Predicted SEED Role

"Type IV fimbrial biogenesis protein FimT" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (203 amino acids)

>UW163_RS00705 general secretion pathway protein GspH (Ralstonia solanacearum UW163)
MRSDNLPLRRLPARGFTLLELMVTIAVISIMLTLVAPSFSDFLRKQRMLSAADSITSAIG
QARTRALAQNAYVTVAPINGDWANGWQVFSEGQNPNGIYDPSNDTLLSQYDALTNGLKVT
YNSTAYVGGAGNASGNYLIYSPNGYTASKLKQPQVTAAFNVAYQDGNGPSRIVIINALGR
ARTCDPNDATTKTSGTCLTSLSQ