Protein Info for UW163_RS00345 in Ralstonia solanacearum UW163

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 702 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF07715: Plug" amino acids 69 to 169 (101 residues), 75.3 bits, see alignment E=5.3e-25 TIGR01783: TonB-dependent siderophore receptor" amino acids 71 to 700 (630 residues), 341.5 bits, see alignment E=5.7e-106 PF00593: TonB_dep_Rec" amino acids 288 to 672 (385 residues), 147.2 bits, see alignment E=1.4e-46

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 99% identity to rsc:RCFBP_20615)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (702 amino acids)

>UW163_RS00345 TonB-dependent siderophore receptor (Ralstonia solanacearum UW163)
MTSRLAARALSYALAAIPLAVSTLARADATSGAQAAATVDLDETTVTARSQRGFAAGTAE
VGSFRGQSLRDIPATVNVITREALDAQQDRTLYDALRNTAGVTRQQLSGETFDNIAIRGV
TMENRTNFRFNGSMPFFNLMAIPLEDKERVEVLKGVSALYYGYTTPGGIVNLVTKRAGNT
PVTSVGMSIDNNGTAISSVDVARRFGEDNQYGLRFNAAGGKLESPTSGIDGDRQMASVAF
DWKVNSRLSLKADVEYARQVITEQSVVTLPAAKNGVISLPAMPDPTKRLSPDWAKFRANS
TTAMLRADYALNDDWLVTVEGGTSELARTRAFTEIGSVNAVTGKGTISGNRQDGRWTTGH
LRADLNGTQMTGSIKHELTFGVARSEMRQAAVYSSRFTGTQNLYNPVDLGWLPTTGTSIT
AAQRAVDTGVYALDRVTLTQHWQVIAGLRYTSYTSVQAPNRYDASKTTPLGALIYKFTPT
LSAYASYAQGLEAGDRAPNTAANANVAMPPAVSNQKEVGVRYETPLGTQLSAALYEIDRA
ASYTNASNVYVQDGRQRIRGVELNAQGRVTNDLSLLASGGWIDAKFRGVGNGLDGKTPEN
TPRATASLFAEYTLPMLRSVSLNAGAYYVGPRPVNDADQAWLGGTTLFGAGARYVTRLAG
KRTTWQFNVDNLTDKRYWAAAGNNRLAMGAPRVFKLSMKIDL