Protein Info for RPSI07_RS23610 in Ralstonia solanacearum PSI07

Annotation: DNA-protecting protein DprA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 TIGR00732: DNA protecting protein DprA" amino acids 96 to 312 (217 residues), 252 bits, see alignment E=1.8e-79 PF02481: DNA_processg_A" amino acids 103 to 303 (201 residues), 249.5 bits, see alignment E=2.9e-78 PF17782: DprA_WH" amino acids 336 to 395 (60 residues), 69.5 bits, see alignment E=3e-23

Best Hits

KEGG orthology group: K04096, DNA processing protein (inferred from 100% identity to rsl:RPSI07_3308)

Predicted SEED Role

"Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (401 amino acids)

>RPSI07_RS23610 DNA-protecting protein DprA (Ralstonia solanacearum PSI07)
MTDASQVAADAATAPADSLDATRDPAELAAWLRLTETPGIGPVAARQLLAAFGLPQDIFR
QSYAALVKVLPERQARALLAEPDEALAALIERTVAWSAEPGNAIFTLADRGYPPRLLELP
DPPTLLYAKGDLSLLRAAAVGVVGARSATAQGLENARAFAQALSAVNVTIVSGLALGIDA
AAHEGALTGPGSTIAVVGTGLDMVYPARNRALAHRIAEAGLMLSEYPLGMGARAENFPRR
NRLIAGLARGLLVVEAAAQSGSLITARLAAEQGRDVFAIPGSIHSPLAKGCHLLIKQGAK
LVETAADILDELGWGQAPAPATPTPRATARAPAPASAPAARPAATAAETALLDALGFDPV
DLDTLCERTGQTAAILSAQLLALELGGRIERQPGGRFLRLP