Protein Info for RPSI07_RS21705 in Ralstonia solanacearum PSI07
Annotation: acyl CoA:acetate/3-ketoacid CoA transferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to rsl:RPSI07_2897)Predicted SEED Role
"Acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (EC 2.8.3.8)" in subsystem Acetyl-CoA fermentation to Butyrate (EC 2.8.3.8)
MetaCyc Pathways
- acetoacetate degradation (to acetyl CoA) (2/2 steps found)
- acetyl-CoA fermentation to butanoate (5/7 steps found)
- pyruvate fermentation to acetone (3/5 steps found)
- 4-aminobutanoate degradation V (3/7 steps found)
- L-glutamate degradation V (via hydroxyglutarate) (5/10 steps found)
- gallate degradation III (anaerobic) (5/11 steps found)
- L-glutamate degradation XI (reductive Stickland reaction) (2/7 steps found)
- superpathway of Clostridium acetobutylicum solventogenic fermentation (6/13 steps found)
- succinate fermentation to butanoate (1/7 steps found)
- superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation (8/17 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.8.3.8
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (554 amino acids)
>RPSI07_RS21705 acyl CoA:acetate/3-ketoacid CoA transferase (Ralstonia solanacearum PSI07) MQVITAEEAARLVQPGWTVACAGFVGAGHAEAVTHALERRFLATGEPRDLTLVYSAGQGD RATRGVNHFGNPGMTRCVVGGHWRSATRLAALALAEQCEAFNLPQGVLTHLYRAIAGGKP GVLTRIGLHTFVDPRTSLDARYHGAAINARARAAREAGTASWVEYERFRGEDYLFYPRFP LHGVFLRGTAADPRGNISTHEEAFHHELLAMAQAARNAGGIVIAQVRRLVDRHDNLQAIH VPGILVDYVVVAEDPAEHQMTFGEAFNPTYLRPWQGEAIQLREDALEAGAAIETSLHGAL DARTLVQRRAVLELMAQRPRVVNLGVGMPAAVGALAEQEGARGFTLTVEAGPIGGTPADG LSFGASAYPEAVVDQPAQFDFYEGGGIDLAILGLAELDGQGNVNVSLFGEGDDTIVAGVG GFINITQSARALVFMGTLTAGGLQVEAGDGRLRIVREGRLKKIVPAVSHLTFNGAYAARS GIPVRYVTERAVFEMRDDGHGGRRLTLTEIAPGIDLQRDVLDQCAAEVAVAADLREMDHR IFRRGPMCAGPAAA