Protein Info for RPSI07_RS18495 in Ralstonia solanacearum PSI07

Annotation: PHP domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 PF02811: PHP" amino acids 13 to 76 (64 residues), 32.1 bits, see alignment E=7.2e-12

Best Hits

Swiss-Prot: 53% identical to 35NBP_CHRVO: 3',5'-nucleoside bisphosphate phosphatase (CV_1693) from Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)

KEGG orthology group: K07053, (no description) (inferred from 100% identity to rsl:RPSI07_2236)

Predicted SEED Role

"COG0613, Predicted metal-dependent phosphoesterases (PHP family)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (286 amino acids)

>RPSI07_RS18495 PHP domain-containing protein (Ralstonia solanacearum PSI07)
MLKRSASAPINADLHCHSTVSDGLLAPREVAARAAAHGVTLWALTDHDEVGGQAAAREAA
ELLGMDYLPGVEISVTWAGRTLHIVGLGIDPDNAALVQGLERTRSGRGARAEDMAEALGK
LGIHGAYEGALSYAGNPDMISRTHFARFLVEHGHCRDIAEVFDRYLGDGKPGFVPHRWAR
LADAIGWIRGAGGVAVMAHPGRYTLTLLEHDVLFDEFKGFGGEGVEVITGSHTPDQYAYY
ADVARRYGLLASRGSDFHGPGEGRVELGELPPLPDNLTPVWSRWLS