Protein Info for RPSI07_RS06945 in Ralstonia solanacearum PSI07

Annotation: FAD-binding oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01266: DAO
  • amino acids 53 to 454 (402 residues), 244.7 bits, E=3.2e-76

Best Hits

KEGG orthology group: None (inferred from 100% identity to rsl:RPSI07_mp1568)

MetaCyc: 41% identical to tyramine oxidase subunit A (Pseudomonas putida U)
Monoamine oxidase. [EC: 1.4.3.4]; 1.4.3.4 [EC: 1.4.3.4]; 1.4.3.4 [EC: 1.4.3.4]

Predicted SEED Role

"D-amino acid dehydrogenase small subunit (EC 1.4.99.1)" in subsystem Pyruvate Alanine Serine Interconversions or Respiratory dehydrogenases 1 (EC 1.4.99.1)

MetaCyc Pathways

• superpathway of phenylethylamine degradation (8/11 steps found)
• phenylethylamine degradation I (1/2 steps found)
• salidroside biosynthesis (2/4 steps found)
• dopamine degradation (2/5 steps found)
• L-tryptophan degradation X (mammalian, via tryptamine) (1/4 steps found)
• putrescine degradation III (1/4 steps found)
• serotonin degradation (3/7 steps found)
• L-phenylalanine degradation IV (mammalian, via side chain) (4/9 steps found)
• phenylethanol biosynthesis (1/5 steps found)
• aromatic biogenic amine degradation (bacteria) (3/8 steps found)
• noradrenaline and adrenaline degradation (4/13 steps found)

KEGG Metabolic Maps

• Alkaloid biosynthesis I
• Arginine and proline metabolism
• Drug metabolism - cytochrome P450
• Glycine, serine and threonine metabolism
• Histidine metabolism
• Nitrogen metabolism
• Phenylalanine metabolism
• Tryptophan metabolism
• Tyrosine metabolism
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 1.4.99.1

Use Curated BLAST to search for 1.4.3.4 or 1.4.99.1

Protein Sequence (484 amino acids)

>RPSI07_RS06945 FAD-binding oxidoreductase (Ralstonia solanacearum PSI07)
MSDALYVLDGASSRATPSRILNLSRWRRHLLESNVVFQATTIPEDLRLPARVDVVVIGGG
IVGISTAMALAEKGVSVAVCEKGVIAGEQSGRNWGWCRTAHRDLRELPLSIESLRMWRTM
GPKLGMDTGFRQSGILYVAADAHALAKHERWLSQARALLGNDALKSRMTSAAETASLMPG
VSRSAAGGMTGGMYTPADGQAEPERAVPAMALALRARGVRILMPCAVRGIETSAGETSGV
MTERGRIRCTSVVIAGGAWTRLFSASLGIEMPQLAVRASVLCTAPVAGGPEVSACYRTVG
YRKRLDGGYIVAHASRSVAELTPDSFRLFSQYWPVLKTQLGSMDFALGRRFIDALRQPRS
WPLDQPTRFETERMLAPKPVQAHNDIALRDFRALFPKLGPVKIARSWAGYIDVTPDAVPV
ISAAGKIRGLFISAGYSGHGFGLGPAAGRLTADLVVNDQPIVDPHAFRLGRFSDGSRVEL
GEGF