Protein Info for RPSI07_RS06640 in Ralstonia solanacearum PSI07

Annotation: aldo/keto reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00248: Aldo_ket_red
  • amino acids 23 to 255 (233 residues), 171.7 bits, E=9.6e-55

Best Hits

Swiss-Prot: 50% identical to GR_BACSU: Glyoxal reductase (yvgN) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to rsl:RPSI07_mp1490)

MetaCyc: 50% identical to glyoxal/methylglyoxal reductase (Bacillus subtilis subtilis 168)
Aryl-alcohol dehydrogenase (NADP(+)). [EC: 1.1.1.91]; 1.1.1.91 [EC: 1.1.1.91]; Methylglyoxal reductase (NADPH-dependent). [EC: 1.1.1.91, 1.1.1.283]

Predicted SEED Role

"oxidoreductase, aldo/keto reductase family"

MetaCyc Pathways

• methylglyoxal degradation V (3/3 steps found)
• methylglyoxal degradation IV (2/3 steps found)
• superpathway of methylglyoxal degradation (4/8 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.283 or 1.1.1.91

Protein Sequence (283 amino acids)

>RPSI07_RS06640 aldo/keto reductase (Ralstonia solanacearum PSI07)
MQEVTLNNGIRMPILGYGVFQIADASECERCVVDAVQAGYRLIDTAASYRNEEAVGRGLK
RCGVPRDQLFVTSKLWVEDAGYERTHAAIEKSLSRLGLDYLDLYLIHQPFSDVHGSWRAM
EEAYRAGKLRAIGLSNFQPDRLMDIQAFNEVTPAVNQIEVNPFHQQAESVDFMRGLGVQP
EAWAPFAEGRNNLFQNGHLLAVAARHGKTVGQVVLRWLVQRGIVALAKSVRKERMQENLA
VFDFELSDDDMQRISLLETGTSSFFSHRDPAIVKWMSERRHGL