Protein Info for RPSI07_RS05625 in Ralstonia solanacearum PSI07

Annotation: two-component system response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 468 PF00072: Response_reg" amino acids 46 to 156 (111 residues), 90.9 bits, see alignment E=8.9e-30 PF13487: HD_5" amino acids 224 to 390 (167 residues), 138.4 bits, see alignment E=3.3e-44 PF01966: HD" amino acids 241 to 354 (114 residues), 29.6 bits, see alignment E=1.2e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to rsl:RPSI07_mp1251)

Predicted SEED Role

"Response regulator containing a CheY-like receiver domain and an HD-GYP domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (468 amino acids)

>RPSI07_RS05625 two-component system response regulator (Ralstonia solanacearum PSI07)
MITYEADTPRTETTDTTANPRPAEASAQAATVVPPPGEPAVPAPLVLLVDDEPSVLSALR
RLLRPTGYRVLTAESGAAGLELLAAHPVDLIVSDMRMPNMNGAEFLSRARAQSPDTMRIL
LTGYAEIDAAVCAINEGGVYRYLNKPWDDQDLLLTVRHAIEQRTLAREAARLTELTRQQN
HRLQALNAGLESQVEARTEEIRQTVLFLEDAQHDLKSNFTKMARVCANMIELRCGIAGGQ
SMRVGDLARRIALACGLTGLQAQDIFHAALLHGIGKLSLPDGLLRKSLDRLAPEEMQLYL
QHPLRAQMVLTPVPQLQAVAHIIRHQYERYNGRGTPDRLVGEHIPIGARIVALARDYMGL
LAGEIVKQRVPPEQAREMVKAQSGLRYDPLVVVRLLTVLKEMEDVPAVRQIGSAELREGM
RLADDLLTRRGVLLITRDSTVNAHQVEQIRRFETHEDAPFAIMIHADT