Protein Info for RPSI07_RS02385 in Ralstonia solanacearum PSI07

Annotation: AcrB/AcrD/AcrF family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1034 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 332 to 351 (20 residues), see Phobius details amino acids 358 to 378 (21 residues), see Phobius details amino acids 384 to 405 (22 residues), see Phobius details amino acids 429 to 450 (22 residues), see Phobius details amino acids 457 to 479 (23 residues), see Phobius details amino acids 519 to 540 (22 residues), see Phobius details amino acids 846 to 866 (21 residues), see Phobius details amino acids 873 to 893 (21 residues), see Phobius details amino acids 901 to 925 (25 residues), see Phobius details amino acids 946 to 965 (20 residues), see Phobius details amino acids 977 to 1003 (27 residues), see Phobius details PF00873: ACR_tran" amino acids 4 to 1003 (1000 residues), 735.4 bits, see alignment E=5.1e-225

Best Hits

KEGG orthology group: None (inferred from 100% identity to rsl:RPSI07_mp0538)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1034 amino acids)

>RPSI07_RS02385 AcrB/AcrD/AcrF family protein (Ralstonia solanacearum PSI07)
MNISSWSIRNPVPAVLCFVLLTVFGLLGFHKLQIQDFPDMDLPTINISASLEGAAPSQLE
NEVARKIEDKLTSLSKLDHVTTKITDGAVSISVSFKLEKDPQAALSEVRNAVDGARASLP
AEMAAPTVSKSDAAASALLTYAASSTAMDEQDLSWFVDNELSKALLSVKGVSKVERIGGI
DREVRIDLDPALMAGMGLTAETVSTQLKAMQRDRSGGQGDIGGQRQSSRTLVGVGSVQDV
AALTITTGDGRRVRLDQIARVTDGAADRSAYAYLDGKPVIGVQITRAKGNSDVTVLHEVR
RTVAAFAAAHPQVKLTEASNTVAPIEDNYEGSMSMLIEGALLAIVVVWWFLRDGRATLVS
AAALPLSIIPTFGVIWLLGYSLNVVTLLALSLVVGILVDDAIVEIENIERHLRMGKTPFQ
AAMQAADEIGLAVIATTFALVAVFLPTAFMSGIPGLIFRQFGVTASVAVLMSLLVARLLT
PMMAAYLMKAASHIDHDSARMTRYLRWVRACLTGRRRTMLAVGVFLVLSVAMVAVLKTGF
MPLQDKSQTQVKLELAPGATLEQSRTTVLRAEALIRQVSEVKGVFASVGSATDTTGMGGT
SSTADVRSSTLIVDLVPRGERGRKQPAVEDAIRAKLRDLPGVRVSVNNGGNGEKLQITLA
GSDAGALESAASALETQLRMLHGIGNVTSSAALQRPEVQFRPDPARAASLGVTAEAAADA
IRIGTYGDYSTSLPKLNLPERQITLRARIDPALRQDLDAIGQLRVAGTHGSVTVASVGTL
SIGSGPSQIDRIDRERNVTLSVELNGRTLGEVNREAQQLSALAHLPAGVHQVEQGELQNM
GELFQSFGLAMAIGVFCVYAVLVLLFHDFLQPATILCALPLSLGGALFSLLVTRMSFSMP
ALIGLLMLMGIVTKNSILLVEYAIMARREHGMRRLEALMDACHKRARPILMTTIAMGAGM
LPNALGLGAEPSFRQPMAIVVIGGLLASTLLSLLVIPVVFTYVDDFEQWLRRRFRRTAAA
EATDLPRALGSDAR