Protein Info for RPSI07_RS01820 in Ralstonia solanacearum PSI07

Annotation: [acyl-carrier-protein] S-malonyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00698: Acyl_transf_1
  • amino acids 13 to 311 (299 residues), 119.4 bits, E=1.2e-38
  • amino acids 383 to 606 (224 residues), 104.5 bits, E=4e-34
• TIGR00128: malonyl CoA-acyl carrier protein transacylase
  • amino acids 383 to 658 (276 residues), 312 bits, E=2.2e-97

Best Hits

KEGG orthology group: K00645, [acyl-carrier-protein] S-malonyltransferase [EC: 2.3.1.39] (inferred from 100% identity to rsl:RPSI07_mp0411)

Predicted SEED Role

"Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)" in subsystem Fatty Acid Biosynthesis FASII or mycolic acid synthesis (EC 2.3.1.39)

MetaCyc Pathways

• superpathway of fatty acids biosynthesis (E. coli) (50/53 steps found)
• superpathway of fatty acid biosynthesis II (plant) (38/43 steps found)
• superpathway of fatty acid biosynthesis I (E. coli) (14/16 steps found)
• fatty acid biosynthesis initiation (type II) (3/3 steps found)
• superpathway of fatty acid biosynthesis initiation (4/5 steps found)
• fatty acid biosynthesis initiation (mitochondria) (2/4 steps found)
• fatty acid biosynthesis initiation (plant mitochondria) (1/4 steps found)
• mycobactin biosynthesis (2/11 steps found)
• pederin biosynthesis (2/14 steps found)
• bryostatin biosynthesis (2/19 steps found)
• mupirocin biosynthesis (1/26 steps found)
• corallopyronin A biosynthesis (2/30 steps found)

KEGG Metabolic Maps

• Fatty acid biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.39

Use Curated BLAST to search for 2.3.1.39

Protein Sequence (660 amino acids)

>RPSI07_RS01820 [acyl-carrier-protein] S-malonyltransferase (Ralstonia solanacearum PSI07)
MPYIAQGQKSSVVFMLPGQGCQFYQMGRELYQNNPVFHRWMNELDTLVRPELGHSVIAEI
YHDNNARSKTFDDIRLSHPAIFMIEYALGKTLIEQRITPDYLLGTSLGELAAAALADVLP
LPEAIRFVTRQGQLFHRRRSPATEGAMLAILSEASLYQQTPLLRDHCDIAAYNASSLIVV
SGQSARIADAERHLSSRDIVFQRLPVNQAFHSHHIDFLQPEVEALASQLSLRQARIPVIS
CHSTETLDRLTADHFWHTIRQPIRFSQTLARIEREAAERGESLIYLDLGPSGTLANLIKQ
NLRDRKLPQIFPVLSPFGRDLEKFDEVLALGRALQPLPATVTAPVQETPRQVQQPEPTPV
RQVQQPVLAPRPMMQPTAGPKRVYVFPGQGSQRVGMGAALFEQFPDHLAKADEILGYSLQ
TLCLEDPDQRLSNTRYTQPALYTVSALAFLSKQRQDPRKPDFLAGHSLGEYCALFAAGAF
PFETGLKLVKKRGELMARATGGSMAAVIGRAPDEVNALLSRHGLDALDIANYNSQSQVVL
AGPVDALGRAREILQEQGVTMIPLTVSAPFHSRYMQSAMEEFGEYLRQFSYSPLHTPVIS
NIHAAPYRDEDLIDNLTRQICGSVRWLDTVQYLIRQGEFECEELGPGNVLSKLVNSIRNA