Protein Info for RPSI07_RS00495 in Ralstonia solanacearum PSI07

Annotation: MATE family efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 62 to 85 (24 residues), see Phobius details amino acids 104 to 126 (23 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details amino acids 176 to 195 (20 residues), see Phobius details amino acids 201 to 222 (22 residues), see Phobius details amino acids 253 to 277 (25 residues), see Phobius details amino acids 294 to 314 (21 residues), see Phobius details amino acids 329 to 358 (30 residues), see Phobius details amino acids 372 to 393 (22 residues), see Phobius details amino acids 403 to 424 (22 residues), see Phobius details amino acids 430 to 449 (20 residues), see Phobius details PF01554: MatE" amino acids 29 to 190 (162 residues), 105.1 bits, see alignment E=3.2e-34 amino acids 258 to 418 (161 residues), 67.8 bits, see alignment E=9.2e-23 TIGR00797: MATE efflux family protein" amino acids 29 to 431 (403 residues), 210.7 bits, see alignment E=1.7e-66 PF14667: Polysacc_synt_C" amino acids 143 to 268 (126 residues), 33.9 bits, see alignment E=3.3e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to rsl:RPSI07_mp0111)

Predicted SEED Role

"Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (476 amino acids)

>RPSI07_RS00495 MATE family efflux transporter (Ralstonia solanacearum PSI07)
MSGEASARPAPARMTDGPIAGTLFALFLPILFGNLMQALNGSVNAMWVGHTLGEAALAAA
ANANAVISFVVAVVMGIGMAASILIGQSLGAKDIAQAKRVVGTGATFFVGLAVLIALAAA
VLTGRIVARMQAPPEVLPLAVAYLRVLFLAMPFQAAYIFLTILLRSTGDSKTPFRFQIVC
VGLDIALNPLLIVGWGPLPALGIAGSATATLMAQGIGLMALAGRLYRTRHILCLRADETH
LLRPDPRILKALIVKGLPMGLHMAVVSLAMVMMMSLVNRFGAQLSAAYGACLHLWNYIQL
PVLAMGMTVTPMAAQNLGARRLDRVGRIALAGIALNVTMAGGMVLVSQCFSGAVLGMFLP
ARMETLQAAQHINAMVAWSFIPFGVTFVLASIIRASGTAMPPLVILFVALWCIRLPAAAV
LMNAWGADALWASFGLGSVSAMLMSMAYYRWAGWRAAFTPIEVSAPVREDQGTARC