Protein Info for QEN71_RS42135 in Paraburkholderia sabiae LMG 24235

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF00126: HTH_1" amino acids 8 to 66 (59 residues), 43.7 bits, see alignment E=2.1e-15 PF03466: LysR_substrate" amino acids 96 to 298 (203 residues), 45 bits, see alignment E=8.5e-16

Best Hits

Swiss-Prot: 69% identical to NODD_BRASP: Nodulation protein D (nodD) from Bradyrhizobium sp. (strain ANU 289)

KEGG orthology group: K14657, LysR family transcriptional regulator, nod-box dependent transcriptional activator (inferred from 97% identity to bph:Bphy_7723)

Predicted SEED Role

"Nodulation protein D (transcriptional regulator, LysR family)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (304 amino acids)

>QEN71_RS42135 LysR family transcriptional regulator (Paraburkholderia sabiae LMG 24235)
MRFKGLDLNLLVALDALMTQRNLTVAAQNINLSQPAMSAAVGRLRDYFSDDLFVMRGREF
VPTARALELAGPVREALSHIQFSIISRDVFQPAKSNRRFRVCLSDFMTLVYFQDVVKRVA
REAPSVSFELLFPDDEPGELLRRGDADFLILPELLLADSHPKAALFEEKLVCVGCPTNKQ
LSRRLPLEKYMSMGHVTVRFGRARRPSIDEFFLLDLGLKRREEVVVPTFDLVPSMLSRTN
RIATIPMRLARHFAEVVPLRIVQVPLPLSSFTESIQWPALHNADPASIWMRELLLQEAQS
LVAG