Protein Info for QEN71_RS38580 in Paraburkholderia sabiae LMG 24235

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF20434: BD-FAE
  • amino acids 94 to 208 (115 residues), 65.2 bits, E=6.6e-22
• PF07859: Abhydrolase_3
  • amino acids 108 to 314 (207 residues), 247.2 bits, E=1.5e-77

Best Hits

Swiss-Prot: 37% identical to YR526_MIMIV: Putative alpha/beta hydrolase R526 (MIMI_R526) from Acanthamoeba polyphaga mimivirus

KEGG orthology group: None (inferred from 95% identity to bph:Bphy_5601)

Predicted SEED Role

"Lipase (EC 3.1.1.3)" (EC 3.1.1.3)

MetaCyc Pathways

• triacylglycerol degradation (2/3 steps found)
• retinol biosynthesis (2/7 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.3

Use Curated BLAST to search for 3.1.1.3

Protein Sequence (342 amino acids)

>QEN71_RS38580 alpha/beta hydrolase (Paraburkholderia sabiae LMG 24235)
MKALKPLVLAAVLAANAVIASAAPATAQPTPDRVTSEFLKQLNSGTGPALNTLPPAKARQ
VLVDAQNSVKVDLSGIDVSNRTIEQDGISVPITIVRPQGATGTLPVFMFFHGGGWILGDF
QTHERLVRDLVVQSGAVAVFVNYTPSPEARYPVAINQAYAATRWVAAHGNEIGVDGSRLA
VVGNSVGGNMAAVVSLMAKDKQGPQIRFQGLMWPVTDANFNDGSYLAYKDKHFLTRAMMQ
WFWDAYTQDPAQRAQIYASPLRASEEELKGLPPALIQVAQFDVLRDEGEAYGRKLDAAGD
EVTTTRYNGTIHDFGLLNALAADAPTQAATKQLANEIKTRLK