Protein Info for QEN71_RS37740 in Paraburkholderia sabiae LMG 24235

Annotation: EAL domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 512 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 228 to 252 (25 residues), see Phobius details PF12792: CSS-motif" amino acids 37 to 227 (191 residues), 97.9 bits, see alignment E=5.8e-32 PF00563: EAL" amino acids 260 to 489 (230 residues), 220.1 bits, see alignment E=3e-69

Best Hits

KEGG orthology group: None (inferred from 86% identity to bph:Bphy_5670)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (512 amino acids)

>QEN71_RS37740 EAL domain-containing protein (Paraburkholderia sabiae LMG 24235)
MLALIVTVVCGACVLVTAALWARHADQAAIRERESLIAGDMVASIDRILDSVVSRAHLEL
STLPGRPCPLVEHRLSELQSYVLYVRSVNLVANHNIYCSSALGPIDVPLTAYLSPAATRF
TLDLLSGTPQQPQTPVMPLYVPTSKDTGLLYLVEASYLADTLAHGVRYEAGDVVLVVTND
RALDARGETIAADSVASLRGTRVSSPRWGFSIVVVAAPSFVAHTQWKFGLLAGAVAILIN
LLIAAAYLIAFAPRRLLLSAVRRALKHGQLHFAYQPVVEIATRRITGVEALIRWTHPRWG
AVSPAAFMTEVERSSVLASVTRFALQRATDDIIQKTDIRPLRIAINVAPMDLERKDFVAD
VLAVKEKLPADITLVLEVTERFLIDKHPRTDVIFNMLKAHGVRFAIDDFGTQHSNLDLLG
RFPFDYVKIDGQFVRQVDRQGCELIRAIAAVSKHYGMEVIAEGVETESQHEALRNLGIPY
GQGYLYQRPVPVSQLFADTGANVLTTRTRVTH