Protein Info for QEN71_RS37690 in Paraburkholderia sabiae LMG 24235

Annotation: PAS domain S-box protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 845 PF13185: GAF_2" amino acids 43 to 176 (134 residues), 42.5 bits, see alignment E=3.9e-14 PF01590: GAF" amino acids 44 to 175 (132 residues), 28.2 bits, see alignment E=1.2e-09 TIGR00229: PAS domain S-box protein" amino acids 217 to 345 (129 residues), 65.9 bits, see alignment E=1.9e-22 amino acids 345 to 469 (125 residues), 60.7 bits, see alignment E=7.6e-21 PF00989: PAS" amino acids 221 to 336 (116 residues), 50.4 bits, see alignment E=1e-16 amino acids 349 to 460 (112 residues), 35.5 bits, see alignment E=4.5e-12 PF08448: PAS_4" amino acids 226 to 340 (115 residues), 27.4 bits, see alignment E=1.7e-09 amino acids 361 to 466 (106 residues), 37 bits, see alignment E=1.8e-12 PF13426: PAS_9" amino acids 231 to 339 (109 residues), 53.6 bits, see alignment E=1.1e-17 amino acids 361 to 462 (102 residues), 41.3 bits, see alignment E=7.7e-14 PF08447: PAS_3" amino acids 372 to 455 (84 residues), 30.5 bits, see alignment E=1.8e-10 PF00512: HisKA" amino acids 477 to 539 (63 residues), 39.5 bits, see alignment 2.4e-13 PF02518: HATPase_c" amino acids 588 to 700 (113 residues), 78.2 bits, see alignment E=3.4e-25 PF00072: Response_reg" amino acids 725 to 834 (110 residues), 65.7 bits, see alignment E=2.1e-21

Best Hits

KEGG orthology group: None (inferred from 91% identity to bph:Bphy_5679)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (845 amino acids)

>QEN71_RS37690 PAS domain S-box protein (Paraburkholderia sabiae LMG 24235)
MNASQDRQIDTTDTTTLLNRERSTNARLRKLIDAHSRIAAAKLDLDRFLSLVTDSLLELV
PAAHASVVEWVDGEDMVYRACSGTIAHHVGLRLKRDGSLSGLCSLEKHLLYSVDTADDPR
VDAAACRRVGAASMIVAPLLYQSEVAGVVKLMAGSASAFSNEDIETLERITSLVASGMAH
QRVFAENRALIEQNTITIARLRTEISLREAADSKLEASLRRRRLVLDTTHDAFVCTDADG
IIIEWNDAATRTFGYARDAVMGRPILDTLFPARCKARYAELDVFRISPEPHPEESSHRSR
TELIARRIDGNEFPAELSVCPVQFDGHVELAYFVRDVTERFSARELDKRFRVLVDAIKDY
AITMLDSQGNITTWSAGSTQVMGYAPNEVLGQSASLFYTPEDVAAGRPQRDLQLAAREGR
IEMEEWRVRKNGTIFWANIITTALRDPNGALQGFAKITRDMSRRRRLEELEASSQRMSQF
LALLGHELRNPLAPLRNAVSMLQLKSADHHGFVPEHELIDRQLSHLTRLVDDLLDAGRVT
LGRVQIEPKPVSMQAIAQLSIEGSAPLLAARDQTLDVVMPDTPMYIEGDLTRMVQVVQNL
LNNASKFSPAGASIGLQVFRSGRLLAIRIYDSGRGIDPDAIDAIFNLFVQETPTEEQADK
SGLGIGLTLARAIVDLHGGHIEAHSEGRGKGSVFTVWLPECNHVIADEGKRDEEPAPAQA
VDLKVMVVDDNIDSADSMATLVQVLGHEAHAVYDGAAAIDLAHTLQPDLVLLDLSMPKMT
GFEALPHIRKALTASGAVIAAMTGLGTSEDRARTEAAGFDLHLTKPVDLPELEGVLQIAV
KHVRD