Protein Info for QEN71_RS37180 in Paraburkholderia sabiae LMG 24235

Annotation: tetratricopeptide repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 573 transmembrane" amino acids 316 to 337 (22 residues), see Phobius details PF13432: TPR_16" amino acids 420 to 472 (53 residues), 18.2 bits, see alignment 1.2e-06 amino acids 482 to 540 (59 residues), 23.6 bits, see alignment 2.5e-08 PF14559: TPR_19" amino acids 485 to 537 (53 residues), 25 bits, see alignment 7.6e-09

Best Hits

KEGG orthology group: None (inferred from 96% identity to bph:Bphy_5779)

Predicted SEED Role

"Adenylate cyclase (EC 4.6.1.1)" in subsystem cAMP signaling in bacteria (EC 4.6.1.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.6.1.1

Use Curated BLAST to search for 4.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (573 amino acids)

>QEN71_RS37180 tetratricopeptide repeat protein (Paraburkholderia sabiae LMG 24235)
MDLVESCRLIQDNEVEAAGRWRKYKARIEHDIVPTHRGRLIRTEGDGLMVTFVELRDALA
ATFAIQRASDETNAGLPPATHMLLRMGLHVTELYEDERDVYGRGVNLAARLYTLAGPGEI
VVSAQVRDQLTPELDADIEDLGECHLKHFDQPVRAYRIGPPGPRPVIEPGAAFLPELRPT
IAVIPFASRGGEAEQQVLGEVMADEIISSLSRTAELQVISRLSTTTFRERDATLDEISAF
LGARYVLSGAYRSWGDQIVLVVELAEAKSRHILWTQSIKGRATHIMLGEDELIDRIVAET
SSAIIDRELQRARSQALPSLASSTLLMSAIVLMHRGVSHDFHRARDMLEALIERARRQAL
PHAWLGKWHVLRFNRGWTDDRVGQAQAALDCTRRALDADPDCSLALTIDGFVHTNLLKQL
DVGQRRYESALDVNPNDSLAWLLKGTLLAFEGEGEQAVDATERALRLSPLDPLRYFYESL
GATAALSAGRYERAVELAQRSLRVNRTNTSTLRALAIAQALLGDLEAARQTVQEVLVLDP
TLTVKSYLDRSPSGAYATGKIWSEALRQAGLPA