Protein Info for QEN71_RS36765 in Paraburkholderia sabiae LMG 24235

Annotation: type III secretion system outer membrane ring subunit SctC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 602 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF03958: Secretin_N" amino acids 108 to 169 (62 residues), 31.2 bits, see alignment E=2.1e-11 amino acids 177 to 354 (178 residues), 42.1 bits, see alignment E=8.2e-15 TIGR02516: type III secretion outer membrane pore, YscC/HrcC family" amino acids 314 to 601 (288 residues), 313.4 bits, see alignment E=1.1e-97 PF00263: Secretin" amino acids 443 to 601 (159 residues), 126.1 bits, see alignment E=1.1e-40

Best Hits

KEGG orthology group: K03219, type III secretion protein SctC (inferred from 56% identity to bug:BC1001_6043)

Predicted SEED Role

"Type III secretion outermembrane pore forming protein (YscC,MxiD,HrcC, InvG)" in subsystem Type III secretion systems, extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (602 amino acids)

>QEN71_RS36765 type III secretion system outer membrane ring subunit SctC (Paraburkholderia sabiae LMG 24235)
MKLTFRRRAIAAALLMMGLTAAHAAPISWRPGEVHISVESRDLKDVLRDFAASQGIIATI
APNVQGTVSGRFDLPPRRFIDTMAATFGFVWFYDGSVLSISTADDVTTKVIKLDFAGTQS
LRATLKQIGLDTDRFPIVYDPEQGVALITGPHRLIQLVDEVAARLDQNANRRTGSEVRAF
PLRYGWAADHTITVNGKTQVVPGVAHVLASLYHPERDSDQQGTSRGSADGTANLQQVNPY
ADVQGGTNGGSPYNSNGVNPPLPDVFAGVAAAGGGPVGAMPGGGYGGTAGGASGGGQGSG
QGGGRAATAAVPEGAGSLPVIQADARTNSVLIRDLPDRVGQYQQLIDRLDVKRRMVEIEA
HIIEIDDGALKQLGVDWHAHSSHFDFQTGSGSANSNNFNGTVSPTFSSLDTAGNLVATAT
PTGGSLTAVVGDAGRYLLTRIDALEQTNLARIDASPKVATLDNVEAVMNNKTQFFIPVSG
FTSSNLFSVQVGNTLRVLPMVVDANGAQQIKLQVHVEDGQPTGNSVKDIPEIRTSEINTE
AVVSEGQSLLIAGYRVDNDSNLNTGVPVLSKIPVLGALFRSRTHQSSHMERLVLLTPRVI
EF