Protein Info for QEN71_RS36070 in Paraburkholderia sabiae LMG 24235
Annotation: class II aldolase/adducin family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 48% identical to ALD2_RHORT: 5-(methylthio)ribulose-1-phosphate aldolase (ald2) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
KEGG orthology group: K01628, L-fuculose-phosphate aldolase [EC: 4.1.2.17] (inferred from 50% identity to mmw:Mmwyl1_4174)MetaCyc: 48% identical to 5-(methylthio)ribulose-1-phosphate aldolase (Rhodospirillum rubrum)
RXN-21316 [EC: 4.1.2.62]; 4.1.2.62 [EC: 4.1.2.62]
Predicted SEED Role
"Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases"
MetaCyc Pathways
- 5'-deoxyadenosine degradation II (4/4 steps found)
- 5'-deoxyadenosine degradation I (2/3 steps found)
- S-methyl-5-thio-α-D-ribose 1-phosphate degradation III (3/5 steps found)
- lactate biosynthesis (archaea) (3/5 steps found)
- D-arabinose degradation II (2/4 steps found)
- L-fucose degradation I (2/4 steps found)
- nucleoside and nucleotide degradation (halobacteria) (2/6 steps found)
- superpathway of fucose and rhamnose degradation (5/12 steps found)
- superpathway of pentose and pentitol degradation (23/42 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 4.1.2.17
Use Curated BLAST to search for 4.1.2.17 or 4.1.2.62
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (224 amino acids)
>QEN71_RS36070 class II aldolase/adducin family protein (Paraburkholderia sabiae LMG 24235) MNGTALTEDSLRAGIVHTMREMVRLGINQGTSGNVSARWRDGFLITPSGVPAAQLEADTI VWLPLDIDASAPVFDEKRPSTEWRFHRDILRARPEIEAVVHTHSNAATAMSIHGRDIPAH HYMVAAAGGNSIRCAPYATFGSQALSDHAVAALQNRTACLLAHHGVIALGADLTRALWLA NEVEVLAQQYLLAATLGVPPVLSDEQMDEVVHRFSHYGVQRKRP