Protein Info for QEN71_RS35340 in Paraburkholderia sabiae LMG 24235
Annotation: aminotransferase class III-fold pyridoxal phosphate-dependent enzyme
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 59% identical to BFAT_VARPD: Beta-phenylalanine transaminase from Variovorax paradoxus
KEGG orthology group: K01845, glutamate-1-semialdehyde 2,1-aminomutase [EC: 5.4.3.8] (inferred from 66% identity to bpy:Bphyt_6417)Predicted SEED Role
"Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)" in subsystem Experimental tye or Heme and Siroheme Biosynthesis (EC 5.4.3.8)
MetaCyc Pathways
- adenosylcobalamin biosynthesis II (aerobic) (31/33 steps found)
- adenosylcobalamin biosynthesis I (anaerobic) (31/36 steps found)
- superpathway of heme b biosynthesis from glutamate (9/10 steps found)
- tetrapyrrole biosynthesis I (from glutamate) (6/6 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 5.4.3.8
Use Curated BLAST to search for 5.4.3.8
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (454 amino acids)
>QEN71_RS35340 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme (Paraburkholderia sabiae LMG 24235) MTTSTLSAAQPAAPRELTTPAEALAAAAHAFAARNPKSARQYELATGVMPGGNTRSVLFY EPFPLAMTKGEGCRLWDADSHEYLDFIAEFSAGIYGHSDPQIRRAIDAALDDGLNLSGHN LLESRLAKAVCERFTSLQSVRFTNSGTEANLMMLAAARAFTGRSKVVVFVGGYHGGVLTF GRGPNAVNVPHEFLYARYNDVNSVARLLHDNPSEVAAILVEPMQGASGCIVGDRDFLKGL RELATAHGALLMFDEVMTSRLAPGGLQSTLEIVPDLTSLGKYIGGGMSFGAFGGRADIMQ LFDPRRSGALQHAGTFNNNVMTMAAGFTGLTQVYTPEAALALTARGDTLRDALNARFSAA NVALRFIGVGSLMNLQITDRPVRSVRDIDASLNVFKDLFFFHLLENGIYIARRGYVVLSL PVGDAETARFEAAVASFIERYGHLLPKSKETDRQ