Annotation: tetratricopeptide repeat protein
These analyses and tools can help you predict a protein's function, but be skeptical.
For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect.
For other types of proteins, the error rates may be much higher.
MetaCyc and Swiss-Prot have low error rates,
but the best hits in these databases are often quite distant,
so this protein's function may not be the same.
TIGRFam has low error rates.
Finally, many experimentally-characterized proteins are not in any of these databases.
To find relevant papers, use PaperBLAST.
Protein Families and Features
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495
PF13676: TIR_2 "
amino acids 9 to 131 (123 residues), 87 bits, see alignment
E=1.3e-27
PF13374: TPR_10 "
amino acids 188 to 217 (30 residues), 15.9 bits, see alignment (E = 8.8e-06)
amino acids 230 to 259 (30 residues), 27.6 bits, see alignment (E = 1.9e-09)
amino acids 272 to 312 (41 residues), 30.6 bits, see alignment
2.1e-10
amino acids 313 to 353 (41 residues), 36.4 bits, see alignment
3.2e-12
amino acids 355 to 395 (41 residues), 44.5 bits, see alignment
8.8e-15
amino acids 397 to 438 (42 residues), 32.5 bits, see alignment
5.5e-11
amino acids 439 to 478 (40 residues), 24.7 bits, see alignment
1.5e-08
PF13432: TPR_16 "
amino acids 195 to 262 (68 residues), 20.6 bits, see alignment
E=4.5e-07
amino acids 278 to 344 (67 residues), 24.8 bits, see alignment
E=2.1e-08
amino acids 362 to 428 (67 residues), 15.7 bits, see alignment
E=1.6e-05
amino acids 410 to 467 (58 residues), 20.8 bits, see alignment
4e-07
PF13424: TPR_12 "
amino acids 229 to 302 (74 residues), 64.6 bits, see alignment
E=6.5e-21
amino acids 275 to 345 (71 residues), 65.8 bits, see alignment
E=2.7e-21
amino acids 315 to 385 (71 residues), 73.3 bits, see alignment
E=1.3e-23
amino acids 359 to 430 (72 residues), 74.5 bits, see alignment
E=5.2e-24
amino acids 401 to 468 (68 residues), 64.3 bits, see alignment
E=8.4e-21
PF13181: TPR_8 "
amino acids 231 to 263 (33 residues), 17.8 bits, see alignment (E = 2.5e-06)
amino acids 319 to 345 (27 residues), 18.4 bits, see alignment (E = 1.6e-06)
amino acids 359 to 387 (29 residues), 20.2 bits, see alignment (E = 4.2e-07)
PF13176: TPR_7 "
amino acids 233 to 264 (32 residues), 21.6 bits, see alignment (E = 1.5e-07)
amino acids 275 to 307 (33 residues), 15.7 bits, see alignment (E = 1.1e-05)
amino acids 317 to 350 (34 residues), 18.8 bits, see alignment (E = 1.1e-06)
amino acids 359 to 389 (31 residues), 23.5 bits, see alignment (E = 3.5e-08)
amino acids 442 to 466 (25 residues), 19.6 bits, see alignment (E = 6.4e-07)
PF17874: TPR_MalT "
amino acids 318 to 483 (166 residues), 41.3 bits, see alignment
E=1e-13
PF14559: TPR_19 "
amino acids 366 to 428 (63 residues), 27.9 bits, see alignment
E=2.1e-09
Best Hits
Predicted SEED Role No annotation
Sequence Analysis Tools PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Search structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (495 amino acids) >QEN71_RS35255 tetratricopeptide repeat protein (Paraburkholderia sabiae LMG 24235)
MTDKPTYDVFVSHSSNDRAAASRVARALKDAGVKLWFDEWTLVPGADWTQAIAKALSDVQ
CVIFILGPGKLTSWQQADLNAIEQRRKSDSDVSIVPVLLPGADLNLLPSALSNWQMLDLR
NEDTFESNIRRFADSFKAAKVGKATDVSVYLESLIATLKELDLDTLPTALTSLVGAGNAQ
GEQTEGLASVFNAVGGSLREQGDLARAELLYRKALECDQQTSTPNPQNAANFLNNIASVL
RDQGRLEEALGYLKQALAIDSENRDGDRPNYANRLNNMGSVLLDLGRTREALGYFSQALA
IDMRTLGPDHPDVANRLSNVGSALRDLGELDEARDYFQRSLEIDTQLLGPEHPTVANRLN
NIGSVLRDQGRFDEALSIFEEALAIDQRTFGNEHPRVANRLSNMGSVMAALNRADEAEEL
LNRALAIDEKMLGPNHPDTAITLNNLANLFIRQGKYAEARGTLQRAYNSSCQSVGAAHWL
SQALSANMDSLSGKL