Protein Info for QEN71_RS33885 in Paraburkholderia sabiae LMG 24235

Annotation: sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 374 PF00005: ABC_tran" amino acids 19 to 161 (143 residues), 117.7 bits, see alignment E=1.6e-37 PF17912: OB_MalK" amino acids 235 to 288 (54 residues), 46.6 bits, see alignment 1.4e-15 PF08402: TOBE_2" amino acids 281 to 354 (74 residues), 44.7 bits, see alignment E=3e-15 PF03459: TOBE" amino acids 296 to 353 (58 residues), 27.6 bits, see alignment E=7.2e-10

Best Hits

Swiss-Prot: 58% identical to MALK_VIBVY: Maltose/maltodextrin import ATP-binding protein MalK (malK) from Vibrio vulnificus (strain YJ016)

KEGG orthology group: K10111, maltose/maltodextrin transport system ATP-binding protein [EC: 3.6.3.19] (inferred from 58% identity to avi:Avi_5741)

MetaCyc: 53% identical to polyol ABC-type transporterATP-binding component MtlK (Pseudomonas fluorescens)
7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]

Predicted SEED Role

"Various polyols ABC transporter, ATP-binding component" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.19

Use Curated BLAST to search for 3.6.3.19 or 7.5.2.M2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (374 amino acids)

>QEN71_RS33885 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC (Paraburkholderia sabiae LMG 24235)
MSAVHLQQIRKAFAGTEVLKGVDIDVKEHEFLVFVGPSGCGKSTLLRSIAGLERIDSGHV
VIEGEDVTELEPSQRGVAMVFQSYALYPHMSVYENIAFGLRMIKLPEAQIKERVHRAAEI
LQIGQLLERRPRALSGGQRQRVAIGRSIVREPKVFLFDEPLSNLDAALRVQMRLELIKLH
KQLNATMIYVTHDQTEAMTMADRIVVLNYGQVEQIGSPLELYRTPRNRFVAGFIGSPKMN
FLDVLVQKKDAQRLTIELPGGAPLDVPCNGDGVEAGQTLVLGIRPEHFIESANGNADSAL
TGEVMVIEHLGSETLLHVRLADERVIQVKGSGESTAEEGQRLQAGFSVRHVHLFREDGLA
LEPGSVVREELRVG