Protein Info for QEN71_RS31420 in Paraburkholderia sabiae LMG 24235

Annotation: hydantoinase/oxoprolinase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 699 PF05378: Hydant_A_N" amino acids 9 to 184 (176 residues), 143.7 bits, see alignment E=7.7e-46 PF01968: Hydantoinase_A" amino acids 206 to 497 (292 residues), 271.8 bits, see alignment E=1.1e-84 PF19278: Hydant_A_C" amino acids 517 to 681 (165 residues), 34.3 bits, see alignment E=2.4e-12

Best Hits

KEGG orthology group: K01473, N-methylhydantoinase A [EC: 3.5.2.14] (inferred from 67% identity to rhi:NGR_b03100)

Predicted SEED Role

"N-methylhydantoinase A (EC 3.5.2.14)" in subsystem Hydantoin metabolism (EC 3.5.2.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.14

Use Curated BLAST to search for 3.5.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (699 amino acids)

>QEN71_RS31420 hydantoinase/oxoprolinase family protein (Paraburkholderia sabiae LMG 24235)
MVASHDKARVGVDIGGTFTDVALELGGALFSTKVLTDYTAPERAIIKGIGIVADKAGIAL
KDIGVIIHGTTLATNALIERRGAKTAFVTTQGFRDTIEMRTENRFEQYDLNIKLPPPLIE
RCDRFTLGERVDAQGGILLAPTEAQIESIVDRIEQGGYESVAIGFIHAYVNGVHERMMRD
AIEKRLPNVSVSISSEVSPQIREFERFNTVCANAYVRPIMKSYLDRLLGKVREAGAVCPL
FIIHSGGGIVSIESASAFPVRLVESGPAGGAIFAAHIAARYDLNSVLSFDMGGTTAKICL
IDDLTPKTANTFEVARTYRFKKGSGMPISIPVVEMVEIGAGGGSIASLDVMRQIRVGPHS
AASEPGPACYQRGGTQPTVTDADLLLGRLDPANFAGGTIQLSTDNAASAMVAEVGGAIDL
NAEEAAYGVAEVVDENMSNAARVHAVESGKDIGDYTMITFGGAGPLHAARLCEKSGIRKF
IVPPGAGVGSAIGFLRAPFGYESVRSASMRFNDFDADALNEIVGQLSEEAVHFARQGSGD
AEPLVEIKAFMRYVGQGWEIPVMIPHRGFTADDRSTFADAFTKAYTQFFGRPIDGLDIEI
VSWAVKASSPMPPVERLQLETSRDAVSAAKTRKIFDAALHRFVDAAIVERGSLKVGECVT
GPAIIVEPETSTLVTSSFDAMVQPDGCLLVVAKELNTSR