Protein Info for QEN71_RS31385 in Paraburkholderia sabiae LMG 24235

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 transmembrane" amino acids 39 to 60 (22 residues), see Phobius details amino acids 78 to 99 (22 residues), see Phobius details amino acids 111 to 129 (19 residues), see Phobius details amino acids 141 to 165 (25 residues), see Phobius details amino acids 178 to 200 (23 residues), see Phobius details amino acids 211 to 230 (20 residues), see Phobius details amino acids 259 to 283 (25 residues), see Phobius details amino acids 296 to 318 (23 residues), see Phobius details amino acids 326 to 346 (21 residues), see Phobius details amino acids 353 to 373 (21 residues), see Phobius details amino acids 385 to 407 (23 residues), see Phobius details amino acids 421 to 439 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 41 to 241 (201 residues), 93.3 bits, see alignment E=1.7e-30 amino acids 250 to 436 (187 residues), 38.2 bits, see alignment E=8.8e-14 PF07690: MFS_1" amino acids 51 to 390 (340 residues), 110.3 bits, see alignment E=1e-35

Best Hits

KEGG orthology group: K03762, MFS transporter, MHS family, proline/betaine transporter (inferred from 44% identity to smt:Smal_2178)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (454 amino acids)

>QEN71_RS31385 MFS transporter (Paraburkholderia sabiae LMG 24235)
MDVNSEAEYLLDDDNNPTARRHETGPTRRTVGRRELKRVVLASVVGSFVEWFEFSVYGYL
AAVMGRVFFPASAPGTQLVASLAAFAIAFFARPFGGFIFGPIGDRYGRKNVLTVTIVLMA
LATFCIGLIPDHDAIGIASPILLVLLRLLQGVSAGGEASGAAIFVAEYCKDRNRTLVTSW
IEVGCMSGFCFGALVAALLSHAFVQTQIDAWAWRLPFLLALPLGAIGLYIRNRLEETPTF
EAAHRAGGFRELFASHKAALLQSSGIIIVTNVTLFIVVTYIPTYLVSTLRLDASTGFTIA
LVSQAFLIVTIPLLAVLADKVGRKTMMLAGSVALAVLAVPCFHLLTVESVGQRLIALLLL
NLCLAALLSCIYSQIPSLFETGVRFTGMAVSYNVSVALFAGTAPMINSWLIQSTGSRMIP
AYYLIAAAVIGLIALACCVDRTGGPMRGDSRSVG