Protein Info for QEN71_RS30750 in Paraburkholderia sabiae LMG 24235

Annotation: mechanosensitive ion channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 16 to 35 (20 residues), see Phobius details amino acids 59 to 81 (23 residues), see Phobius details amino acids 93 to 111 (19 residues), see Phobius details amino acids 140 to 161 (22 residues), see Phobius details amino acids 167 to 187 (21 residues), see Phobius details PF00924: MS_channel_2nd" amino acids 189 to 255 (67 residues), 43.6 bits, see alignment E=1.3e-15

Best Hits

KEGG orthology group: None (inferred from 75% identity to bpy:Bphyt_1945)

Predicted SEED Role

"Small-conductance mechanosensitive channel"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (429 amino acids)

>QEN71_RS30750 mechanosensitive ion channel (Paraburkholderia sabiae LMG 24235)
MVSFDDVARITEAPMHSWLGGIVVSLVAMTIGLVIQRVGARIVMRIARPYPFTTIVLHSI
DMPTRVLLMLLTLGFVFWQAPDTLRFIGPLRDAWAFVLIAAITWLSLRLAGSIGEAIIRA
HPLDAEDNLHARRIHTQARVLARSVMVVIIILGFGGALMMFPSVRQIGASLLASAGVAGL
VAGIAARPVLGNLIAGLQIALAQPIRLDDVVVIQDEWGRIEEITGTYVSVRLWDMRRLVV
PLQWFIEHPFTNWTRSSSQIIGTVFLYVDYRTPLAPLREELGRLLNDAPEWDGSVQVLQM
TDATERALQLRVLVSSADSGLNWDLRCRVREGLLAFVQQHCPQYLPHARAEVTAELDGGE
ALPTMSSAARHGEPAASSTAADTPADPVAVRPSGTRRGNPIRGNGHEERHTPAATDGMYR
GRARALNTH