Protein Info for QEN71_RS30075 in Paraburkholderia sabiae LMG 24235

Annotation: efflux transporter outer membrane subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 486 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 16 to 473 (458 residues), 397.6 bits, see alignment E=3.8e-123 PF02321: OEP" amino acids 74 to 264 (191 residues), 66.3 bits, see alignment E=1.6e-22 amino acids 289 to 471 (183 residues), 90.5 bits, see alignment E=6.1e-30

Best Hits

KEGG orthology group: None (inferred from 92% identity to bph:Bphy_7210)

Predicted SEED Role

"Heavy metal RND efflux outer membrane protein, CzcC family" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (486 amino acids)

>QEN71_RS30075 efflux transporter outer membrane subunit (Paraburkholderia sabiae LMG 24235)
MFTIRGSLVRKAIAVAVAFALTACSTLPHYSQPQTAVPDHFASTPQASAGWSLAAPADAQ
TRGPWWTLFGDDELNQLEAQVDVSNQTVQKAVAQLEAARALVDYQRAGYAPVVTAGASAQ
RYRTSQNVVHKGLAGHTVPDFSAGLAASWEPDLFGRVKDAAVNARDNAQASEADLQSVRL
SVATDLAIDYFNLRSLDRQKKLLDDTVTAYTAALRIVQQQLKDGAIDASAVAQAQTQLES
TRTQDSDIDVQRAQLEHAIATLIGKPASSFSLPPKVQTTALPQIPAGVPSQLLERRPDIA
AAERRVAAANAQIGQARAAFYPNLTLSATAGLESSYFAPWLTASSLFWSLGSQIAGTLFD
GGRRDAVLKNATAQYDGTVADYRQTVLVAFQQVEDQLSSLNTLASEADSQQRATAAADLS
LKLTTNRYQAGAVNYLDVVTAQTIALSNERTAEQIGARRIDASVQLLKALGGGWDRSALT
DAAATD