Protein Info for QEN71_RS30030 in Paraburkholderia sabiae LMG 24235

Annotation: Na+/H+ antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 527 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 31 to 51 (21 residues), see Phobius details amino acids 57 to 76 (20 residues), see Phobius details amino acids 86 to 107 (22 residues), see Phobius details amino acids 113 to 136 (24 residues), see Phobius details amino acids 156 to 177 (22 residues), see Phobius details amino acids 183 to 207 (25 residues), see Phobius details amino acids 214 to 231 (18 residues), see Phobius details amino acids 267 to 289 (23 residues), see Phobius details amino acids 300 to 325 (26 residues), see Phobius details amino acids 350 to 370 (21 residues), see Phobius details amino acids 382 to 405 (24 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 10 to 400 (391 residues), 183.1 bits, see alignment E=3.8e-58 TIGR00831: Na+/H+ antiporter" amino acids 14 to 520 (507 residues), 291.1 bits, see alignment E=7.8e-91

Best Hits

KEGG orthology group: K03316, monovalent cation:H+ antiporter, CPA1 family (inferred from 73% identity to bpy:Bphyt_6974)

Predicted SEED Role

"Na+/H+ antiporter" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (527 amino acids)

>QEN71_RS30030 Na+/H+ antiporter (Paraburkholderia sabiae LMG 24235)
MSAVSAFKLVLLSLIAIIALELIARRLRLPPAAALLVGGAAMAFAPGLPPVVLDPDLVLI
VFLPPLLMDGAYFFVWTDFKRHIKPILLFAIGAVAFTTWIVGVVVHWVVPSLPWAACFAL
GAVVSPPDAVAAKAVLERVALPRRLMVLLEGESLLNDAAGLVLFRFAVAAALTGAFSASH
AALSFAGLAVGGVAVGCVVGFVVVWLLRLLDGDYLIITTSVISCWISYIAGEMLDVSSVI
STVTCGMVLGWHQHEIFSATVRMRGTAFWQVIVFVFEALVFVLIGLSLRGVMLRLGGIDN
ALALLGPAALATVATVVVSRGVWTFGLEAINAVLHRISRRAAPPADWRSASVVSWAGMRG
VVTLAIALSLPETMPGRDLIQFSAFVVILFTVLLQGTTIGLAIRIIRPAADAHASTYLTE
PQAWARLEAAQFEAIKPLVHAPDGSVLHPRLLEQYSYRARLTHEFQDAESFPQEARKAHY
DVVLAAIAAGRAELLRMHRRGLIHDELLHVLERDLDLQEMASRHAQG