Protein Info for QEN71_RS29010 in Paraburkholderia sabiae LMG 24235

Annotation: chemotaxis protein CheA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 771 PF01627: Hpt" amino acids 7 to 93 (87 residues), 69.9 bits, see alignment E=4.6e-23 PF09078: CheY-binding" amino acids 193 to 255 (63 residues), 87 bits, see alignment E=1.8e-28 PF02895: H-kinase_dim" amino acids 378 to 440 (63 residues), 71.9 bits, see alignment E=1.2e-23 PF02518: HATPase_c" amino acids 488 to 624 (137 residues), 60.6 bits, see alignment E=4.7e-20 PF01584: CheW" amino acids 630 to 757 (128 residues), 93.4 bits, see alignment E=2.4e-30

Best Hits

KEGG orthology group: K03407, two-component system, chemotaxis family, sensor kinase CheA [EC: 2.7.13.3] (inferred from 93% identity to bph:Bphy_2974)

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (771 amino acids)

>QEN71_RS29010 chemotaxis protein CheA (Paraburkholderia sabiae LMG 24235)
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVGHPDPEDLAAIFRAAHSIKGGAATFGFT
ALTETTHILESLLDRARNNEIKLRKDMIDTFLETKDVLSGQLADYRASAEPDGAVAAAIC
AKLERLHAESSGAAAAPAAAPAAAPAAAELVAEGHAPEHVVEQAVEAAGEWAENEPAQTG
AASSDAAAGPHLKITLRGVGEKDQELLTEELGNLGRIVGQVKAGGDITLWLESDVSSDDI
TAVCCFVIDESQIVIGRGAAPASGAEQGAPGASESAQSEPAQAVQAGGTASGGAGAPAAV
VQAAPVAAQPAAQAAAQPAAQATPAPAEAAIVTPAAAAQPEASASAPAAAPAAKAAPASA
EGDRKARPAAAANAGEGSSIRVGVEKVDQLINLVGELVITQAMLAETTSTFDPALHDRLF
NGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAAKLGKQVELVTFGQATELDK
SLIERIIDPLTHLVRNSLDHGIETVEARKAAGKDSTGQLVLSAAHHGGNIVIEVSDDGAG
LRRDKILAKAAKQGMSVSDTMTDDEVWNLIFLPGFSTAEQVTDVSGRGVGMDVVKRNIQS
MGGHVEITSQAGKGSTTRIILPLTLAILDGMSVKVGSEIFILPLNFVMESLQPQADDIYT
VANGERVVRVRGEYLPLVALHEVFSVDGARTEPTQGIVTIMQTEGRRFAMLIDELVGQQQ
VVVKNLETNYRKVHGISAATILGDGSVALIVDVAALNRETRASHGAALSLA