Protein Info for QEN71_RS27300 in Paraburkholderia sabiae LMG 24235

Annotation: HlyC/CorC family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details amino acids 63 to 88 (26 residues), see Phobius details amino acids 94 to 114 (21 residues), see Phobius details amino acids 126 to 159 (34 residues), see Phobius details PF01595: CNNM" amino acids 13 to 183 (171 residues), 158.3 bits, see alignment E=2.4e-50 PF00571: CBS" amino acids 279 to 327 (49 residues), 31.6 bits, see alignment 2.5e-11 PF03471: CorC_HlyC" amino acids 347 to 419 (73 residues), 61.3 bits, see alignment E=1.1e-20

Best Hits

KEGG orthology group: None (inferred from 97% identity to bph:Bphy_2654)

Predicted SEED Role

"Magnesium and cobalt efflux protein CorC" in subsystem Copper homeostasis: copper tolerance or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (434 amino acids)

>QEN71_RS27300 HlyC/CorC family transporter (Paraburkholderia sabiae LMG 24235)
MEQLPLWAQIGAVVLLLICSSFFSITETAMMAINRHRLKHLATKGALGAKTTQGLLARTD
ELLSAVLIGNNLFNTIIPVLTTSIALHTFGSNNVVLSIATGIVAFLIIVFAEITPKIVGA
TFPEKIALPASLLIAPLMRVSKPLIWFVNLFANTILRVLHINTKGAHDQRLSTEELRTIV
LESGSFMPTKHRSILLNLFDLENITVDDVMIPRRRIEALDFDAPFEQILHQLETCYHNKL
VVYQGDFDRVLGVLHVRKTLSALHNQELERETLRELLAEPYFVPTGTPVFQQLQFFQESR
HRTALVVDEYGELQGLVTPEDIIEELIGEFTTSVPRSASSRGGWNEAGECIVAGSMPLRE
LNRWLQLKLPTDGPKTLNGLILEILEEIPEGDVCVKIADVKIEVMRSDDQAIRTVKIFRP
GPPPGSKIKRLVGR