Protein Info for QEN71_RS26630 in Paraburkholderia sabiae LMG 24235

Annotation: ATP-dependent DNA helicase RecG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 740 PF17191: RecG_wedge" amino acids 55 to 206 (152 residues), 41.3 bits, see alignment E=3.2e-14 TIGR00643: ATP-dependent DNA helicase RecG" amino acids 71 to 712 (642 residues), 718.9 bits, see alignment E=3.3e-220 PF04851: ResIII" amino acids 312 to 478 (167 residues), 38.2 bits, see alignment E=3.6e-13 PF00270: DEAD" amino acids 315 to 484 (170 residues), 90 bits, see alignment E=3.9e-29 PF00271: Helicase_C" amino acids 530 to 634 (105 residues), 58.8 bits, see alignment E=1.5e-19 PF19833: RecG_dom3_C" amino acids 663 to 725 (63 residues), 44 bits, see alignment E=5e-15

Best Hits

KEGG orthology group: K03655, ATP-dependent DNA helicase RecG [EC: 3.6.4.12] (inferred from 94% identity to bph:Bphy_2523)

Predicted SEED Role

"ATP-dependent DNA helicase RecG (EC 3.6.1.-)" in subsystem DNA-replication (EC 3.6.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-, 3.6.4.12

Use Curated BLAST to search for 3.6.1.- or 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (740 amino acids)

>QEN71_RS26630 ATP-dependent DNA helicase RecG (Paraburkholderia sabiae LMG 24235)
MPLSDTRSPLDTDDDSAPKKRRAARSKAGADADAPDVKDAPKKAKKPAAKKPVLAKTADK
LAKLGLTRDIDLVLHLPMRYEDETSLTPIGELLPGGVEQTEGVVFDNEIAYRPRRQLLVK
MRDDAGDELILRFLNFYGSQVKQMSVGVRLRVRGDVRGGFFGMEMVHPAVRVVDDDTPLP
QALTPVYPSTAGVSQVYLRKAIDNALARTSLPELLPEAVAKQYLQPLEVPELMDAVRTLH
HPNSHSDEAAMIDGTHPAWTRIKFEELLAQQLSLKRAHEERRTRAAPAMPRRAATDEQSL
LTRLMQTLPFSLTGAQQRVCAEISQDLTQAHPMQRLLQGDVGSGKTVVAALAAAQAIDAG
YQAAMMAPTEILAEQHARKLRGWLEPLGVTVAWLAGSLKTKEKRSALEAAALGTAQLVIG
THAIIQDAVEFARLGLVIVDEQHRFGVEQRLALRAKAQNAADGARDFQPHQLMMSATPIP
RTLAMTYYADLDVSTIDELPPGRTPILTKLVSDARREEVIGRVREAALTGRQVYWVCPLI
EESETLQLQTAVETYETLVAALPELKVGLVHGRLTPVEKATVMDAFSRNEVQLLVATTVI
EVGVDVPNASLMVIEHAERFGLAQLHQLRGRVGRGSAASVCVLLYTGPLSMTARARLQTM
RETTDGFEIARRDLEIRGPGEFLGARQSGAAMLRFADLENDGWLIEPAREAATTLLAQYP
NVVTQHLLRWLNTREQYLKA