Protein Info for QEN71_RS23430 in Paraburkholderia sabiae LMG 24235

Annotation: glycogen synthase GlgA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 486 TIGR02095: glycogen/starch synthase, ADP-glucose type" amino acids 4 to 485 (482 residues), 575.5 bits, see alignment E=4.3e-177 PF08323: Glyco_transf_5" amino acids 6 to 244 (239 residues), 261.8 bits, see alignment E=1.7e-81 PF13439: Glyco_transf_4" amino acids 78 to 232 (155 residues), 29.2 bits, see alignment E=2.3e-10 PF00534: Glycos_transf_1" amino acids 291 to 462 (172 residues), 61.6 bits, see alignment E=1.8e-20 PF20706: GT4-conflict" amino acids 301 to 476 (176 residues), 27.3 bits, see alignment E=4.7e-10 PF13692: Glyco_trans_1_4" amino acids 304 to 447 (144 residues), 49.8 bits, see alignment E=1.2e-16

Best Hits

Swiss-Prot: 58% identical to GLGA_FRATN: Glycogen synthase (glgA) from Francisella tularensis subsp. novicida (strain U112)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 96% identity to bph:Bphy_1798)

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.21

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (486 amino acids)

>QEN71_RS23430 glycogen synthase GlgA (Paraburkholderia sabiae LMG 24235)
MTIRALHVASELYPLLKTGGLADVVGALPPALIELGADVRVLLPGFPAVVGGLSDLQPVA
RIGDRFGASDVTLERGTLAANGLIVYVIRAESLYDRSGNPYLDAEHVPYGDNAQRFAMLG
WTAAQLALHLDPAWAPQIVHAHDWHAGLAPAYLKAAAREHGKPPARTIFTVHNLAYQGIF
PAHQFGQLGLPADFFHMSGVEFYGQMSFLKAGLFYSDRITTVSPTYAREIQTLAQGGGLD
GLLSQRSHDLSGILNGVDYSVWQPSTDQLIAGRYTDTRLAGKRACKTALQERFHLAPKSD
ALLFGVVSRLTEQKGLDLLLAALPDIIKRGGQLVVFGTGDPALENGLQRVAQSHPESVAV
ELGFDETLAHQIVAGSDVIAVPSRFEPCGLTQLYALAYGSLPLVHRVGGLADTVVDASLE
NIADDLATGFVFERFEPEALTAAIRRAFALYARRTDWKAAQRRAMRQDFGWGTSAERYLA
LYRELV