Protein Info for QEN71_RS23325 in Paraburkholderia sabiae LMG 24235

Annotation: EAL domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 PF00563: EAL" amino acids 108 to 221 (114 residues), 66 bits, see alignment E=3.5e-22 PF08668: HDOD" amino acids 244 to 300 (57 residues), 34.5 bits, see alignment 1.5e-12

Best Hits

KEGG orthology group: K07181, putative signal transduction protein containing EAL and modified HD-GYP domains (inferred from 94% identity to bph:Bphy_1776)

Predicted SEED Role

"Predicted signal transduction protein" in subsystem Flagellar motility

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>QEN71_RS23325 EAL domain-containing protein (Paraburkholderia sabiae LMG 24235)
MPDPYQDTDEAGRPQTFAQAGEEDEAISSAQFVYVGRQPILDRDGALHAYELLFRASAEN
YAQVSDDAQATAQVVVRTIGSIGVPSVLGTHRGFVNIGRDLLFDDIVHLMEPERFVLEIL
ETVEFDERLIARIAELRRAGFRVALDDVCELSPNLYAALPYADIVKVDFLETDRAQLASL
TQALARHGKTLIAEKVETREDFALARELGFDLFQGYFFARPQVLSSRRTRSSRTSLLRLL
ALLARDAGIVELEAELKRNPNVVMQLLRLVNSSAFGLGRNIASLREAIIATGTRQIARWA
QLLLYAGGGELPWRSDPLVQLAGTRARFMELAARWIQPNDEAFADAAFLTGVFSLVHVLV
DSTPDATLDPLDLSPLIRDAIVERAGPMGALLSIAEAAGEAQDAAAIASAQSLEEFGALT
PIVLAELNLSAAAWFGAHLGD