Protein Info for QEN71_RS23185 in Paraburkholderia sabiae LMG 24235

Annotation: exodeoxyribonuclease V subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 681 TIGR01447: exodeoxyribonuclease V, alpha subunit" amino acids 29 to 669 (641 residues), 468.4 bits, see alignment E=1.9e-144 PF13245: AAA_19" amino acids 171 to 316 (146 residues), 117.1 bits, see alignment E=2.7e-37 PF13604: AAA_30" amino acids 173 to 328 (156 residues), 87.6 bits, see alignment E=3.6e-28 PF00580: UvrD-helicase" amino acids 174 to 237 (64 residues), 27.8 bits, see alignment E=8.1e-10 PF05127: Helicase_RecD" amino acids 186 to 296 (111 residues), 27.8 bits, see alignment E=9e-10 PF13538: UvrD_C_2" amino acids 598 to 644 (47 residues), 50.9 bits, see alignment 4.6e-17 PF01443: Viral_helicase1" amino acids 598 to 644 (47 residues), 24.2 bits, see alignment 1.1e-08

Best Hits

KEGG orthology group: K03581, exodeoxyribonuclease V alpha subunit [EC: 3.1.11.5] (inferred from 86% identity to bph:Bphy_1747)

Predicted SEED Role

"Exodeoxyribonuclease V alpha chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (681 amino acids)

>QEN71_RS23185 exodeoxyribonuclease V subunit alpha (Paraburkholderia sabiae LMG 24235)
MSTFDQPLPDVEVNVPAPEDFSTALAEGFARRVSALARRGGASDDAVRWAARAAFAASRA
TSEGHVCVPLDELAQRYESEVAHVRRALLVSGVASDGMQPAHALRPLVVDGQGRLYLARY
YDYERRLAQSLVDHARGAHDDAVSVDMSPDGLRDRLLRYFGKPQDEQIDWQRVAAVMALS
GRLTIVSGGPGTGKTTTVVGVLACLLDARADLRIALAAPTGKAAQRMQEALLARAGSLPP
ELAARLPQTSFTLHRLLGTGPNGRFRHHRDNPLPYDVIVIDEASMIDVAMATHLFDALAR
DTHLVMLGDKDQLAAVEAGAVFGELSAQPSFTSRGIGSIAAALDIDERRLRDALPTVGND
EPSNHPEPFFDDLFGMPADTPPSSTQTQSAPLADCVVWLERNYRFGLESAIGRLSLAIRR
GAAQEALDLLVINATANPTADSAAPCAAAFHEDVDAAPSERTIHRLAAGFAPYADALATA
LADDAANAASHAPALFEALNRFRILCATRLGARGVDQMNTAMAAQVRRAARVPLAIGAQW
FAGRPIMVTRNDYALGLFNGDIGIALPGADGALRVWFRGADGGLRAVSPAALPPHDTAFA
LTVHKSQGSEFDHAVLMLPSTFSRVLSRELVYTAVTRARERVEVVGARTVLLRAIATPTQ
RDSGLAARIVEAMESTEAGSL