Protein Info for QEN71_RS23065 in Paraburkholderia sabiae LMG 24235

Annotation: translational GTPase TypA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 608 TIGR01394: GTP-binding protein TypA/BipA" amino acids 5 to 600 (596 residues), 964.1 bits, see alignment E=2.4e-294 PF00009: GTP_EFTU" amino acids 5 to 195 (191 residues), 188.8 bits, see alignment E=1.9e-59 TIGR00231: small GTP-binding protein domain" amino acids 6 to 139 (134 residues), 81.3 bits, see alignment E=6.8e-27 PF01926: MMR_HSR1" amino acids 8 to 129 (122 residues), 24.7 bits, see alignment E=5.6e-09 PF03144: GTP_EFTU_D2" amino acids 219 to 290 (72 residues), 39.1 bits, see alignment E=2e-13 PF00679: EFG_C" amino acids 397 to 478 (82 residues), 80.8 bits, see alignment E=1.6e-26 PF21018: BipA_C" amino acids 486 to 594 (109 residues), 162.1 bits, see alignment E=8.7e-52

Best Hits

Swiss-Prot: 66% identical to TYPA_ECOL6: GTP-binding protein TypA/BipA (typA) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K06207, GTP-binding protein (inferred from 99% identity to bph:Bphy_1722)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (608 amino acids)

>QEN71_RS23065 translational GTPase TypA (Paraburkholderia sabiae LMG 24235)
MSRALRNIAIIAHVDHGKTTLVDQLLRQSGTFRENQQIAERVMDSNDIEKERGITILAKN
CAVQYEGTHINIVDTPGHADFGGEVERVLSMVDSVLLLVDAVEGPMPQTRFVTKKALALG
LKPIVVINKIDRPGARIDWVINQTFDLFDKLGATEDQLDFPIVYASGLNGYAGLDPSVRE
GDMRPLFEAILEHVPVRPADPDGPLQLQITSLDYSTYVGRIGVGRITRGRIKPGQQVVLR
FGPEGEILNRKINQVLSFEGLERVQVAEAEAGDIVLINGIEEVGIGATICAPEAPEALPM
ITVDEPTLTMNFLVNSSPLAGKEGKFVTSRQIRDRLMKELNHNVALRVKDTGDETVFEVS
GRGELHLTILVENMRREGYELAVSRPRVVLHEVDGVKHEPYELLTVDVEDGHQGGVMEEL
GRRKGEMLDMASDGRGRTRLEYRIPARGLIGFQGEFMTLTRGTGLMSHVFDEYLPLKEGS
LGERRNGVLISQDDGAAVAYALWKLQDRGRMFVKPGDALYEGMIIGIHSRDNDLVVNPIK
GKQLTNVRASGTDEAVRLVPPVQMSLEYAVEFIDDDELVEVTPQSIRLRKRYLKEHERRR
ASREAAID