Protein Info for QEN71_RS22925 in Paraburkholderia sabiae LMG 24235

Annotation: ribonuclease R

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 818 TIGR02063: ribonuclease R" amino acids 9 to 738 (730 residues), 827.9 bits, see alignment E=7.2e-253 TIGR00358: VacB and RNase II family 3'-5' exoribonucleases" amino acids 64 to 738 (675 residues), 703.1 bits, see alignment E=3.3e-215 PF08206: OB_RNB" amino acids 76 to 133 (58 residues), 81.3 bits, see alignment 7.9e-27 PF17876: CSD2" amino acids 154 to 226 (73 residues), 86.6 bits, see alignment E=2.4e-28 PF00773: RNB" amino acids 248 to 579 (332 residues), 354.5 bits, see alignment E=1.5e-109 PF00575: S1" amino acids 654 to 735 (82 residues), 42.2 bits, see alignment E=2.1e-14

Best Hits

KEGG orthology group: K12573, ribonuclease R [EC: 3.1.-.-] (inferred from 97% identity to bph:Bphy_1697)

Predicted SEED Role

"3'-to-5' exoribonuclease RNase R" in subsystem RNA processing and degradation, bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (818 amino acids)

>QEN71_RS22925 ribonuclease R (Paraburkholderia sabiae LMG 24235)
MSKYPYPIPSREEILGVLRTSETPLAANDIAEALSIKRQEREGFFKRLAAMERDGQIRLD
QRGHYQLTHPSNFVAGRVQGHRDGYGFLIRDDGQDDLFLPTGEMQKVMHNDRVLARIVGY
DRRGRPEGHIVEVTDRANKRVIGRLLNENGALIVVPEEKRIGHDILITQNTKKAKVGQVV
VVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQAALDAAAKLPDEV
RPVDIKHRVDLRDVPLVTIDGEDARDFDDAVYCEPVKVGRGEGFRLIVAIADVSHYVLPD
GGLDVDAIERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLVCDVVITARGEIKAYQ
FYPGVMHSAARLTYTEVAAVLTNTKGPEATRRAALLPHLQNLYGVYKALFAARQKRGAID
FDTTETYIVCNAQGKIEQIVPRHRNDAHKLIEECMLAANVCAADFMKRNKHPGLYRVHAG
PTTERLENLRTFLRGMGLTLGGGDTPHASDYAALMAHIRDRPDAQMLQTMLLRSMQQAVY
SPDNIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILQGRKYEPKAPHGVELNTALSPR
ARAMQAEDEKRTGRGRPNTAIWEELGMHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
GGMVSGVTSFGIFVQLDALFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKSQHRATTAEKASDLGGGPRVRSMERAAQVEGGRRKK
APPAQTAAVKEARAARKAAASKKRAASKSSAKPAHKKR