Protein Info for QEN71_RS22295 in Paraburkholderia sabiae LMG 24235

Annotation: DNA polymerase III subunit gamma/tau

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 769 TIGR02397: DNA polymerase III, subunit gamma and tau" amino acids 3 to 355 (353 residues), 424.2 bits, see alignment E=2.3e-131 PF13177: DNA_pol3_delta2" amino acids 20 to 178 (159 residues), 138.1 bits, see alignment E=7.2e-44 PF00004: AAA" amino acids 42 to 171 (130 residues), 39.8 bits, see alignment E=1.6e-13 PF12169: DNA_pol3_gamma3" amino acids 232 to 357 (126 residues), 82.9 bits, see alignment E=5e-27 PF12170: DNA_pol3_tau_5" amino acids 639 to 749 (111 residues), 33.4 bits, see alignment E=1.1e-11

Best Hits

KEGG orthology group: K02343, DNA polymerase III subunit gamma/tau [EC: 2.7.7.7] (inferred from 88% identity to bph:Bphy_0951)

Predicted SEED Role

"DNA polymerase III subunits gamma and tau (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (769 amino acids)

>QEN71_RS22295 DNA polymerase III subunit gamma/tau (Paraburkholderia sabiae LMG 24235)
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAK
ALNCETGVTSTPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
GHIVSHLERILGEEHIPHEAQALRLLARAADGSMRDALSLTDQAIAYSANQVTEEAVRGM
LGALDQSYLIRLLDALVAGDGTAVLSVADEMALRSLSFSTALQDLASLLHKIAWAQFSPS
SVLEEWPEAGDLRRFADALSPEQVQLFYQIATIGRSELGLAPDEYAGFTMTLLRMLAFEP
APNGGGGGGVTPAGRSTVPAAGAKRSTGAPVAAAPQARASDATAPRAVPTPKAEPVPVQP
QVVRETPEVADPVALEIEAAPVDDAVTPLSANVEASSEPQEKPAPRDEIPTQPAAAPRRA
GGASAALDVLRSAGNKVSTDRGRSAASTSAAAATPAAPAKSAAPRVAVRVPTPDPARRAA
AAAQQESAARTPTPRAAQPQGASAVPPWEDIPPDDYMPASSDDAFFAPSDDNFVPVFDSG
PDDMLVGRSQASAPAAAPAVDIRTLPPAVPLNEIGFDGDWPTLAVTLPLKGISYQLAFNS
ELMAVNGKTLKLNVAVQLYTEPAQIAKLKAALAERLGTEIDVQVELGPVKRTAAVLDSIE
RAKRQQEAEREIGSDPFVQSLIREFGASIVPGSVRPLMPGAEGGQSAAH