Protein Info for QEN71_RS22060 in Paraburkholderia sabiae LMG 24235

Annotation: transcription-repair coupling factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1164 PF17757: UvrB_inter" amino acids 141 to 229 (89 residues), 79.5 bits, see alignment 5.8e-26 TIGR00580: transcription-repair coupling factor" amino acids 159 to 1085 (927 residues), 1050 bits, see alignment E=0 PF21132: MFD_D3" amino acids 382 to 455 (74 residues), 72.7 bits, see alignment 6.7e-24 PF02559: CarD_TRCF_RID" amino acids 484 to 540 (57 residues), 72.1 bits, see alignment 1.2e-23 PF00270: DEAD" amino acids 609 to 769 (161 residues), 89.8 bits, see alignment E=6.1e-29 PF04851: ResIII" amino acids 609 to 765 (157 residues), 37.9 bits, see alignment E=6.1e-13 PF00271: Helicase_C" amino acids 810 to 913 (104 residues), 67.9 bits, see alignment E=3.2e-22 PF03461: TRCF" amino acids 1013 to 1105 (93 residues), 92.6 bits, see alignment E=5.5e-30

Best Hits

KEGG orthology group: K03723, transcription-repair coupling factor (superfamily II helicase) [EC: 3.6.4.-] (inferred from 87% identity to bac:BamMC406_1859)

Predicted SEED Role

"Transcription-repair coupling factor" in subsystem DNA-replication or Transcription factors bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.-

Use Curated BLAST to search for 3.6.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1164 amino acids)

>QEN71_RS22060 transcription-repair coupling factor (Paraburkholderia sabiae LMG 24235)
MPDIAASTQSSSSTPVALVKAGQRFVFDGTHGSSDAMLIARYHHAYKAQMPLLAVVCASA
VDAQRLSQELAFFAPNARVRLLPDWETLPYDSFSPHQDLVSERLATLHDLGEGRCDILLV
PATTALYRMPPASFMAAYTFSFSQGERLDEAKLKAQLTLAGYEHVSQVVRPGEYCVRGSL
IDLFPMGSPLPYRIDLFDDQVDSIRAFDPDSQRSLYPVKDVRLLPGREFPFDEAARTAFR
SRWREVFEGDPSRASIYKDIGNGVPSAGIEYYLPLFFEETATLFHYLPDASQLVFVGDLD
AAIKRFTADTKQRHGFLSHDRDRPILEPKRLFLSDDDFYTFAKPFARLSLPGNAGGGWAV
PLPNLAIDRHADDPVSALRAWLATTPNRVLFAAESAGRRETIAQLLADNELRPASADSYD
DWLTSDARFALGVAPLSNGFAVPAEGIAILTETELYGPLARKAGRRRQEQASNVDSMVRD
LSELKVGDPVVHSQHGIGRYMGLVTMDLGEGETEFLHLEYQGDSKLYVPVSQLHVISRYS
GADPESAPLHSLGSGQWEKAKRKAAQQIRDTAAELLNLYARRALREGHAFALDPRDYVKF
AESFGFEETPDQAAAIAAVIGDMTSGKPMDRLVCGDVGFGKTEVALRAAFIAVMGGKQVA
LLSPTTLLAEQHTQTFTDRFSDWPVRIAELSRFKTGKEVSASIQQINEGSVDIVIGTHKL
LSSDVQFKRLGLVIIDEEHRFGVRQKEALKALRAEVDVLTLTATPIPRTLGMALEGLRDF
SVIATAPQKRLAIKTFVRREEDGVIREAMLRELKRGGQVYFLHNEVETIENRRQMLEALV
PEARIAVAHGQMHERELERVMRDFVAQRANVLLCTTIIETGIDVPSANTILIHRADKFGL
AQLHQLRGRVGRSHHQAYSYLLVHDPQGLTKQAQRRLEAIQQMEELGAGFYLAMHDLEIR
GTGEVLGDKQSGEIHEIGFQLYTDMLNDAVKALKNGKEPDLTAPLAATTEINLHTPAILP
ADYCGDVQERLSLYKRLANCEHNDSIDGIQEELIDRFGKMPPQAHALVETHRLRLAAKPL
GISKIDAGEAVIALQFVPNPPVDAMRIIEMVQKHKHIKLAGQDKLRIETRSPDFTVRVST
VKETLRALGTPSKGAADQRVASSR