Protein Info for QEN71_RS21720 in Paraburkholderia sabiae LMG 24235

Annotation: polysaccharide biosynthesis tyrosine autokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 730 transmembrane" amino acids 23 to 43 (21 residues), see Phobius details amino acids 438 to 458 (21 residues), see Phobius details PF02706: Wzz" amino acids 12 to 103 (92 residues), 46.1 bits, see alignment E=1e-15 PF13807: GNVR" amino acids 381 to 460 (80 residues), 95.9 bits, see alignment E=2.2e-31 TIGR01007: capsular exopolysaccharide family" amino acids 519 to 711 (193 residues), 141.2 bits, see alignment E=1.6e-45 PF01656: CbiA" amino acids 542 to 715 (174 residues), 33.4 bits, see alignment E=8e-12 PF13614: AAA_31" amino acids 545 to 661 (117 residues), 46.4 bits, see alignment E=8.9e-16

Best Hits

KEGG orthology group: K08253, non-specific protein-tyrosine kinase [EC: 2.7.10.2] (inferred from 97% identity to bph:Bphy_1061)

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.2

Use Curated BLAST to search for 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (730 amino acids)

>QEN71_RS21720 polysaccharide biosynthesis tyrosine autokinase (Paraburkholderia sabiae LMG 24235)
MQARTEEEDVVLGQLLQVIIDDIWWLIGIAATIVAMAGFYCYVAKPVYSADAHVRVEASD
NTSQALTQTQTGATISTGQNTIPTDAEIEMIKSRGVVAPVVQQMKLNFSVTPKTIPILGS
LAARLATPGQPAKAWLGLGSYAWGGEVAEVDSIDVTPALEGKKLILTAMDNGRYTLMTPD
GQLLLRGEAGEPAQGGGVTMLVNKLVARPGTQFTVMRANDLDAIGAFQSAINVQEQGKQT
GVISISLEDQSPEHAAAVANALAQSYLLEHIRTKQADASRMLDFLKSEEPRLKSDLERAE
AALTAYQSKSGSINASDEAKVYLEGSVQYEQQISSLRLQISQLEQRYGDDHPMIKAAQEQ
MAELQAQRTKYADRFRDLPATEVKAVQLQRDAKVAEDIYVLLLNRVQELSVQKAGTGGNV
HIVDAALRPGSPIKPKKVLILSAATILGLIVGTGFVFLRRNMFKGIDDPETVERTFHLPV
YGLVPLSAEQALLENAAVRGGTRQRAVLANAKPKDVCIESLRSLRTSMQFTLQDARNRIV
MFTGPLPGVGKSFLTINLGVLLAHSGKRVLMIDGDMRRGALEKHLGGSPDNGLSELLSGQ
ISLEEAVRATEIDNLAFISCGRRPPNPSELLMSPRLPQYLEGLAKRYDVILIDTPPVLAV
TDASIIGGYAGSTFFVVRSGMHSEGEIADALKRLHSSGVHVQGAIFNAMPPRARGNYDRH
YAAVQEYLST